N/A N=479 Randomized Single-blind Prevention

Text Intervention to Facilitate Secure Storage and Disposal of Prescription Opioids

Opioid Misuse

Bottom Line

View on ClinicalTrials.gov: NCT05503186 ↗

Enrolled (actual)

479

Serious AEs

0.0%

Results posted

Mar 2026

Primary outcome: Primary: Percentage of Participants Who Securely Stored Their Opioid Medication During Treatment — 48; 29; 140; 181 Participants — p=0.003

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Text Message (Other); Standard of Care (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Wake Forest University Health Sciences
Primary completion: Dec 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Percentage of Participants Who Securely Stored Their Opioid Medication During Treatment	48; 29; 140; 181	0.003 sig
PRIMARY Percentage of Participants Who Disposed of Their Unused Opioid Medication	21; 12; 76; 88	0.070

Summary

The proposed study aims to develop and implement a text message intervention that will instruct and motivate individuals to securely store opioid medications during treatment and subsequently dispose of unused medications following treatment. It is relevant to public health as it is expected to meet the critical need of reducing the diversion of prescription opioids for nonmedical use. The proposed research is relevant to National Institute on Drug Abuse's priorities to develop and implement theoretically based, prevention interventions that can be scalable in healthcare settings to elicit population-level impacts to address the opioid crisis.

Eligibility Criteria

Inclusion Criteria

18 years or older
able to read and speak English
owning a cell phone with the capability of receiving short message service (SMS) text messages
receiving an opioid prescription within the past 14 days

Exclusion Criteria

17 years or younger
not able to read and speak English
does not own a cell phone with the capability of receiving SMS text messages
has not received an opioid prescription within the past 14 days

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05503186). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.