N/A
N=41
Evaluation of a Cone-beam CT Scanner for Image Guided Radiotherapy
Head and Neck Cancer · Lung Cancer · Breast Cancer · Abdominal Cancer · Pelvic Cancer
Bottom Line
View on ClinicalTrials.gov: NCT05524454 ↗Enrolled (actual)
41
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcome: Primary: Image Quality — 6.6; 9.8; 11.2; 8.9 standard deviation of HU values
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Novel CBCT Imaging (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Varian, a Siemens Healthineers Company
- Primary completion
- Aug 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Image Quality |
6.6; 9.8; 11.2; 8.9; 7.1; 7.6 | — |
| SECONDARY Accuracy of Radiation Dose Calculation on HyperSight CBCT |
1.1; 6.5 | — |
| SECONDARY Qualitative Assessment of Novel CBCT Images for Contouring Organs at Risk |
47; 70 | — |
Summary
This is a feasibility study investigating the image quality of a new, high-performance cone beam CT (CBCT) used for on-couch imaging during radiotherapy treatments.
Eligibility Criteria
Inclusion Criteria
- The patient will be treated with external beam photon radiotherapy at Maastro for head-and-neck cancer, stage I lung cancer, stage II-IV lung cancer, left breast cancer, or tumours in the abdominal or pelvic region.
- Age ≥ 18 years
- Ability to understand the requirements of the study and to give written informed consent, as determined by the treating physician
- Provision of written informed consent
Exclusion Criteria
- Patient is pregnant
Data sourced from ClinicalTrials.gov (NCT05524454). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.