N/A N=228,831 Randomized Single-blind Prevention

Precision Vaccine Promotion in Underserved Populations

Influenza · Vaccine Hesitancy

Bottom Line

View on ClinicalTrials.gov: NCT05537441 ↗

Enrolled (actual)

228,831

Serious AEs

0.0%

Results posted

Oct 2024

Primary outcome: Primary: Number of Participants Vaccinated at the End of the Campaign Period — 33357; 854 Participants — p=0.216

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Text messaging (Behavioral)
Age: Pediatric, Adult, Older Adult · 0+ yrs
Sex: All
Sponsor: University of Southern California
Primary completion: Mar 2023

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Participants Vaccinated at the End of the Campaign Period	33357; 854	0.216
SECONDARY Heterogeneity of Treatment Effects for Demographics	44742; 1129; 77001; 1921	0.34

Summary

Previous studies have shown that low-cost, behavioral nudges through texting can increase influenza vaccination uptake compared to usual care. However, there are limited studies that evaluate the effect of decreasing barriers to scheduling, especially within safety net populations. The setting for this study, DHS, is the second largest public delivery system in the country and serves approximately half a million diverse patients that are eligible for vaccinations annually. This pilot study (one arm in a larger randomized controlled trial) will examine the effect of text messages highlighting MediCal health plan transportation resources (vs standard text messaging) on influenza vaccination rates in adults during the 2022-2023 flu season.

Eligibility Criteria

Inclusion Criteria

Los Angeles County Department of Health Services (LACDHS) primary care patients over 6 months of age

Exclusion Criteria

LACDHS patients less than 6 months of age

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05537441). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.