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N/A N=112 Randomized Single-blind Prevention

Co-Use of Opioid Medications and Alcohol Prevention Study

Alcohol Drinking · Opioid Use

Enrolled (actual)
112
Serious AEs
Results posted
Sep 2025
Primary outcome: Primary: Alcohol Use Reductions — 11; 12; 1; 1 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Alcohol-targeted Brief Intervention-Medication Therapy Management (Behavioral); Standard medication counseling (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Utah
Primary completion
Aug 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Alcohol Use Reductions
11; 12; 1; 1; 1; 2
PRIMARY
Opioid Medication Use
12; 17; 1; 0; 1; 0

Summary

Previous research, including that of this team, shows that a significant portion of those regularly using opioids-particularly filling opioids at community pharmacies-also are involved in the co-use of alcohol. This study proposes to adapt a previously developed intervention for opioid medication misuse; test its acceptability, feasibility, and preliminary efficacy; and identify barriers and facilitators to large-scale research and system-level implementation. Results of this study will directly inform a fully-powered subsequent multisite trial.

Eligibility Criteria

Inclusion Criteria

  • English speaking
  • ≥18 years
  • Not receiving cancer treatment
  • Current alcohol use
  • Prescribed an opioid medication

Exclusion Criteria

  • SA 2 exclusion
  • Are pregnant
  • Cannot provide collateral contact information for ≥2 persons
  • Do not have a reliable land line or mobile phone to be contacted by study staff
  • Are filling only buprenorphine
  • Plan to leave the area for an extended period of time in the next 3-months, or
  • Have experienced a psychotic and/or manic episode in the last 30 days
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05599672). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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