N/A N=35 Treatment

Endometriosis Group Care

Endometriosis · Pelvic Pain

Bottom Line

View on ClinicalTrials.gov: NCT05622955 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2026

Primary outcome: Primary: PROMIS Pain Interference SF 8a — -1.62 t-score

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Peer Empowered Endometriosis Pain Support (PEEPS) (Other)
Age: Adult · 18+ yrs
Sex: Female
Sponsor: Washington University School of Medicine
Primary completion: Dec 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY PROMIS Pain Interference SF 8a	-1.62	—
SECONDARY PROMIS Physical Function SF10a	1.12	—
SECONDARY Female Sexual Function Index	1.51	—
SECONDARY Endometriosis Health Profile-30	-12.58	—
SECONDARY PROMIS Anxiety SF7a	-1.84	—
SECONDARY PROMIS Depression SF8b	-2.48	—
SECONDARY Patient Global Impression of Change (PGIC)	37.5	—
SECONDARY Modified Every Day Discrimination Scale	67.6	—

Summary

The goal of this clinical trial is to test the effectiveness of the Peer Empowered Endometriosis Pain Support (PEEPS) program in people living with endometriosis-related pelvic pain. The main question[s] it aims to answer are: * Is PEEPS effective at decreasing pain interference and improving patient-reported quality of life outcomes? * What are the barriers and facilitators to PEEPS implementation? Participants will engage in eight weekly 2-hour sessions led by an endometriosis specialist, pain psychologist, pelvic floor physical therapist, and yoga instructor. At these sessions they will participate in peer support, education, mindfulness, and yoga.

Eligibility Criteria

Inclusion Criteria

Age 18-48 years
Operative confirmation of endometriosis
Chronic pelvic pain (defined as pain perceived to originate from the pelvis, lasting ≥6 months)
No plan to have surgery in next 12 weeks
Be able to attend eight 2-hour weekly sessions on the Washington University campus

Exclusion Criteria

Non-English speaking
Currently pregnant
Severe physical impairment
History of hip or spine surgery
Opioid use ≥ 5 days in the past 3 months, other than for the 6-week post-operative period
Current or history of psychiatric disorder with psychosis
Vulvadynia or vaginismus

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05622955). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.