N/A
N=100
SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups
Smoking Cessation
Bottom Line
View on ClinicalTrials.gov: NCT05645354 ↗Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Feasibility as Assessed by Number of Participants Recruited for the Study — 100 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- SmokefreeSGM (Behavioral); SmokefreeTXT (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- The University of Texas Health Science Center, Houston
- Primary completion
- Jul 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility as Assessed by Number of Participants Recruited for the Study |
100 | — |
| PRIMARY Feasibility as Assessed by Number of Participants That Completed Month 1 Visit |
35; 34 | — |
| PRIMARY Feasibility as Assessed by Number of Participants That Completed Month 3 Visit |
22; 20 | — |
| PRIMARY Feasibility as Assessed by Number of Participants That Completed Month 6 Visit |
19; 16 | — |
| PRIMARY Acceptability as Assessed by Number of Participants Who Completed Qualitative Interviews |
16; 9 | — |
| SECONDARY Number of Participants That Quit Smoking |
3; 7 | — |
| SECONDARY Number of Participants That Quit Smoking |
3; 7 | — |
| SECONDARY Number of Participants That Quit Smoking |
3; 7 | — |
Summary
The purpose of this study is to test the feasibility and acceptability of Smokefree Sexual and Gender Minority (SGM), an SGM-tailored version of the SmokefreeTXT text messaging program
Eligibility Criteria
Inclusion Criteria
- Self-identify as an LGBTQ+ individual
- Currently live in the United States
- Have smoked at least 100 cigarettes in their lifetime, smoke every day, and smoke greater than or equal to 5 cigarettes a day
- Are willing to quit smoking in the next 15 days
- Have a cell phone number with an unlimited short message service (SMS) plan
- Have a positive cotinine saliva test to indicate their smoking status
Exclusion Criteria
- Have a prepaid cell phone plan (pay-as-you-go plan)
- Have a cell phone number that does not work and/or is registered to someone else
- Have inadequate equipment/devices (i.e., webcam, speakers, mic) for participating in telehealth sessions via Microsoft Teams, Webex, or Zoom AND cannot meet in-person
- Pregnant or breastfeeding persons (nicotine patches are not generally recommended to this groups since nicotine can affect fetal and neonatal brain development)
- Contraindication for nicotine patches. Absolute contraindications include: severe eczema or serious skin conditions, allergy to nicotine patches, pregnancy, breastfeeding, heart attack in the past 2 months, ongoing angina, peptic ulcer disease, arrhythmia, or uncontrolled blood pressure. Potential contraindications include: stroke in the past 6 months, insulin therapy, and a current diagnosis of liver, kidney, or heart disease. Study participants reporting a potential contraindication will require approval from their primary care provider and/or other treating physician (e.g., psychiatrist) to use nicotine patches. If the request is denied or not returned in 2 weeks, potential study participants will be excluded from the study.
- Current use of tobacco cessation medications
- Enrollment in another smoking cessation study
- Non-English speakers
Data sourced from ClinicalTrials.gov (NCT05645354). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.