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N/A Completed N=100 Randomized Double-blind Supportive Care

Using Aromatherapy in Substance Use Disorder

Source: ClinicalTrials.gov NCT05660434 ↗
Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Jan 2025
Primary outcomePrimary: Examine Feasibility (Eligible Participant Recruitment) — 45; 55 Participants

Summary

The purpose of this clinical trial study is to see if Bergamot, an aroma therapy essential oil, has any effect on comfort, ease, and stress. Participants will be asked to use a bergamot aroma inhaler, which is a small tube about the size of a lipstick container, at least three times a day for one week. Comfort, ease, and stress will be measured with self-report survey at the beginning and at the end of the week. In addition, participants will be asked to complete a daily logbook to record use of the inhaler. The study lasts for one week (7 days). The aims of this study are to explore the effects of Bergamot essential oil on comfort, ease, and stress in adults in a substance use disorder (SUD) treatment program, and to evaluate the feasibility of this type of aroma therapy intervention.

Outcome Measures

OutcomeResultp-value
PRIMARY
Examine Feasibility (Eligible Participant Recruitment)
45; 55
PRIMARY
Examine Feasibility (Eligible Participant Enrollment)
45; 55
PRIMARY
Examine Feasibility (Participant Retention)
43; 54
PRIMARY
Examine Fidelity of the Intervention
45; 55
SECONDARY
Change in Perceived Comfort Level
116.29; 114.17; 117.91; 114.84
SECONDARY
Change in Perceived Ease Level
53.04; 53.88; 57.21; 55.58
SECONDARY
Change in the Depression, Anxiety, and Stress Scale (DASS-21)
20.49; 20.28; 18.54; 21.34
SECONDARY
Visual Analogue Scale to Assess Daily Perceived Comfort
66.72; 49.02; 80.68; 55.71

Eligibility Criteria

Inclusion Criteria

  • Participants can be at any level of treatment, including peer recovery coach program at West Virginia University Comprehensive Opioid Addiction Treatment (COAT) program
  • All participants must be alert and oriented
  • Provide written consent
  • Able to read and write English

Exclusion Criteria

  • Have a medical history of asthma or other serious respiratory disease
  • Known allergy to citrus.
  • Dislike of Bergamot
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05660434). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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