Phase 4
Completed N=52
Regional Anesthesia Following Pediatric Cardiac Surgery
Atrial septal defect · ventricular septal defect · Pain, Procedural
Source: ClinicalTrials.gov NCT05688670 ↗
Enrolled (actual)
52
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcomePrimary: Total Amount of Opioid Medications Administered — 0.44; 0.83 MME/kg — p=0.001
◆ Published Evidence
Emerging
6citations · ~6 / year
Combined Pecto-intercostal Fascial Plane and Rectus Sheath Blocks Versus Local Infiltration for Pain Management Following Pediatric Cardiac Surgery: A Randomized Clinical Trial.
Summary
The purpose of this study is to evaluate pain control following pediatric cardiac surgery with the use of local anesthesia via an ultrasound guided regional anesthetic technique compared with surgeon delivered wound infiltration.
Linked Publications
-
Combined Pecto-intercostal Fascial Plane and Rectus Sheath Blocks Versus Local Infiltration for Pain Management Following Pediatric Cardiac Surgery: A Randomized Clinical Trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Total Amount of Opioid Medications Administered |
0.95; 1.57 | 0.004 sig |
| SECONDARY Total Amount of Opioid Medications Administered |
0.95; 1.57 | 0.004 sig |
| SECONDARY Postoperative Pain Intensity AUC |
45.0; 94.5 | 0.002 sig |
Eligibility Criteria
Inclusion Criteria
- Children less than 18 years old
- Presenting for primary atrial septal defect or ventricular septal defect repair
- Informed consent / assent provided
Exclusion Criteria
- Patients on opioid therapy at the time of surgery
- History of sternotomy
- Planned postoperative intubation
- Current diagnosis of a chronic pain syndrome.
Data sourced from ClinicalTrials.gov (NCT05688670) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.