N/A
N=25
Anti-Snoring Appliances and Airway Manipulation in Patients Undergoing Anesthetic Sedation
Airway Obstruction · Snoring · Sedation Complication
Bottom Line
View on ClinicalTrials.gov: NCT05748626 ↗Enrolled (actual)
25
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Combined Total Number of Airway Interventions During an Anesthetic Sedation Case — 7; 5 Airway Interventions
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Anti-snoring device (Device); No anti -snoring device during their procedure. (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Northwestern University
- Primary completion
- Aug 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Combined Total Number of Airway Interventions During an Anesthetic Sedation Case |
7; 5 | — |
| SECONDARY Maximum End-tidal CO2 |
41; 44.4 | — |
| SECONDARY Number of Instances SpO2 Value < 92% |
.6; .1 | — |
| SECONDARY Minimum End-title CO2 in mmHg |
7; 6.7 | — |
| SECONDARY Percent Time During the Case the SpO2 is Below 92% |
.7; .1 | — |
| SECONDARY Maximum SpO2 Value During the Case |
99.9; 99.5 | — |
| SECONDARY Minimum SpO2 Value During the Case |
91.3; 94.8 | — |
| SECONDARY Heart Rate Maximum |
80.8; 82.5 | — |
| SECONDARY Heart Rate Minimum |
53.4; 58.5 | — |
| SECONDARY Maximum Systolic Blood Pressure |
140; 152.2 | — |
| SECONDARY Minimum Systolic Blood Pressure |
88.9; 88.1 | — |
| SECONDARY Maximum Diastolic Blood Pressure |
75.3; 77.1 | — |
| SECONDARY Minimum Diastolic Blood Pressure |
51.2; 53.2 | — |
| SECONDARY Minimum Mean Blood Pressure |
65.1; 64.6 | — |
| SECONDARY Maximum Mean Blood Pressure |
98.4; 104.5 | — |
| SECONDARY Reintubation in the Post Anesthesia Care Unit |
0; 0 | — |
| SECONDARY Surgical Length of Time |
2.5; 2.6 | — |
Summary
Would patients using an anti-snoring appliance intraoperatively require less airway manipulation, interventions, and rescue maneuvers during anesthetic sedation cases compared to those who do not? The investigators will use anti-snoring appliance devices (specifically the FDA approved Zyppah) to attempt to relieve tissue obstructions that cause snoring during sleep. The application of the devices to the body is less invasive than other common intraoperative rescue airway devices (e.g. nasal trumpets and oral airways) which are not designed to be patient specific.
Eligibility Criteria
Inclusion Criteria
- Adult patients (age 18-89 years old)
- Undergoing procedures below the umbilicus requiring anesthetic sedation without an invasive airway
- a STOP-BANG (survey) score of 2 or greater.
Exclusion Criteria
- Patients who are unable to consent
- Non-English speaking
- Those requiring general anesthesia.
Data sourced from ClinicalTrials.gov (NCT05748626). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.