N/A N=133 Mechanisms of Upper Airway Obstruction
Obstructive Sleep Apnea
Primary: Pharyngeal Critical Pressure (Pcrit) — 1.26; -1.42; -1.06 cm H2O — p=.80
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=56 The Articulated Oral Airway as an Aid to Mask Ventilation
Mask Ventilation · Airway Obstruction Upper · Airway Management
Primary: Expiratory Tidal Volume (Breaths 6-10) — 4.46; 3.21; 3.12; 3.48 ml/kg
N/A N=164 Soiled Airway Tracheal Intubation and the Effectiveness of Decontamination by Paramedics
Airway Management · Intubation, Intratracheal · Laryngoscopy
Primary: Difference in First-pass Intubation Success Rates Before and After SALAD Training — 44; 74 Participants
N/A N=55 Progression of Airway Obstruction in Childhood Asthma
Asthma
Primary: Airway Wall Thickness — 1.5; 1.5; 1.4; 1.6 mm — p=0.2
N/A N=59 Assessment of Airway Obstruction in Infants With Lower Respiratory Infections
Bronchiolitis · Respiratory Syncytial Virus Infections
Primary: Lung Function — 0.071; -3.179; 0.186; -3.345 Z score — p=0.0020
N/A N=31 Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome
Sleep-disordered Breathing · Snoring
Primary: Pleural Pressure (Pes) — 9.3; 4.4 mmHg
N/A N=50 Treatment of Nasal Airway Obstruction Using the Aerin Medical Device
Nasal Obstruction
Primary: Improvement in NOSE Score — 54.8 units on a scale — p=<0.0001
N/A N=2 Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
Sleep Apnea, Obstructive · Hypotonia · Child, Only
Primary: Ability to Tolerate Measured by Percent of Participants With Protocol Goal — 50 percent of participants
N/A N=51 Correlation Endoscopic View of Airway Obstruction With RRa in OSA Patients Under DEX Monitored With SedLine EEG
Obstructive Sleep Apnea (OSA)
Primary: Number of Subjects in Which Electroencephalogram (EEG) Signals is Collected — 47 Participants
N/A N=26 Respiratory Impedance and Obliterative Bronchiolitis
Hematopoietic Stem Cell Transplantation · Obliterative Bronchiolitis
Primary: Airway Distensibility With Lung Inflation After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) — 0.07 1/cmH2O*s
N/A N=1,283 Airway Limitation Study: Study In Primary Care Centers Of Chronic Bronchitis In Long-Term Cigarette Smokers Of At Least 40 Years Of Age With Symptoms Of Cough And Shortness Of Breath
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With a Post-bronchodilator FEV1/FVC <=70% Versus Participants With a Postbronchodilator FEV1/FVC >70% — 308; 893 participants
N/A N=3,004 Pragmatic Airway Resuscitation Trial
Cardiac Arrest
Primary: Number of Patients Alive at 72 Hours After Episode. — 230; 275 Participants
N/A N=50 One-Lung Ventilation in the Morbidly Obese Patient: Comparison of Double Lumen Versus Bronchial Blockers
Obesity
Primary: Time Taken for Endotracheal Tube Placement Procedure. — 3.4; 4.1 minutes
N/A N=15 Upper Airway Physical Therapy for the Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea Syndrome
Primary: Delta of Apnea Hypopnea Index (AHI) as Measured by Polysomnography (PSG) — 4.27 events per hour
N/A N=26 Effect of Added Varnum Mouthpiece on Pharyngeal Collapsibility and Sleep Apnea Severity in Mouth Breathers.
Obstructive Sleep Apnea
Primary: Sleep Apnea Severity as Measured by Apnea-hypopnea Index (AHI) — 16.4; 15.8 Events/hour
N/A N=360 Apneic Oxygenation During Airway Management in Pediatric Patients
Hypoxia
Primary: Time to First Event: Pulse Oximetry at 95%, or Successful Intubation — 106; 169 seconds
N/A N=50 EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
Obesity, Morbid
Primary: Non Hypoxic Apnea Time — 216.7; 258.2 seconds — p=0.005
N/A N=50 The Effect of Prolonged Inspiratory Time on Pulmonary Mechanics in Obese Patients
Hypoxia
Primary: PaO2(Partial Pressure of Oxygen in Arterial Blood) — 178.71; 198.04; 185.25; 202.54 mmHg
Phase 2 N=13 DAW1033B2 in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA)
Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 33; 20.4 events/hour of sleep — p=0.47
N/A N=36 Incidence of Sleep-disordered Breathing and Upper Airway Collapsibility in Postpartum Patients and Its Intervention
Sleep Disordered Breathing · Upper Airway Collapsibility · Upper Airway Obstruction
Primary: Apnea-hypopnea Index (AHI), Defined as the Number of Apneas and Hypopneas Per Hour of Sleep — 4.5; 7.7 Apneas and hypopneas per hour of sleep
Phase 2 N=11 DAW1033D in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA)
Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 21.6; 37.9 events/hour of sleep — p=0.56
N/A N=21 Positive Airway Pressure for the Treatment of Asthma
Asthma · Sleep Apnea
Primary: Asthma Control Test — 19.3; 19.8; 19.1; 19.6 units on a scale — p=0.8
N/A N=30 Predictors of the Ability to Protect the Airway in Long-term Ventilated Patients
Swallowing Disorder · Aspiration · Long Term Ventilation
Primary: Muscle Strength — 20; 10 participants
Phase 4 N=18 The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
Airway Complication of Anaesthesia · Healthy
Primary: Upper Airway Closing Pressure — -9.83; -10.77 cm H20
N/A N=122 Study of the AERin Medical Vivaer® ARC Stylus for Nasal AirWAY Obstruction
Nasal Obstruction
Primary: Change in Nasal Obstructive Symptom Evaluation (NOSE) Scores From Baseline to 3 Months — -47.6 score on a scale
N/A N=20 Treatment Outcome Using Vivaer Stylus to Treat Nasal Airway Obstruction
Nasal Obstruction
Primary: Change in NOSE Score — -44.5 units on a scale
N/A N=126 The Natural History of Small Airways Physiology in Diseased and Healthy States
Asthma · COPD · Interstitial Lung Disease
Primary: FEV1 — 3.03; 2.32; 3.18; 2.76 L
N/A N=119 Airway Protective Mechanisms in PD (R01)
Parkinson Disease
Primary: Respiratory Sensitivity — 0.22; 0.22; 0.21; 0.22 scores on a scale / CmH2O — p=<.0001
N/A N=34 Positive Airway Pressure Program
Sleep Apnea, Obstructive
Primary: Participant Providing Feedback — 26 Participants
N/A N=317 Obstructive Sleep Apnea in World Trade Center Responders
Obstructive Sleep Apnea
Primary: Adherence to CPAP Pre-crossover — 1; 0.89 Hours/night