N/A
N=30
Multi-Component Prehabilitation for Major Elective Surgery
Frailty · Functional Recovery · Prehabilitation
Bottom Line
View on ClinicalTrials.gov: NCT05752474 ↗Enrolled (actual)
30
Serious AEs
3.6%
Results posted
Dec 2025
Primary outcome: Primary: Feasibility of the Prehabilitation Program — 19 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Exercise (Behavioral); Nutrition (Behavioral); Meditation (Behavioral); Cognitive Behavioral Intervention (Behavioral)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- Beth Israel Deaconess Medical Center
- Primary completion
- Jan 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility of the Prehabilitation Program |
19 | — |
| SECONDARY Change in 5-chair Stand Test Time |
-3.4 | — |
| SECONDARY Change in Dominant Handgrip Strength |
1.6 | — |
| SECONDARY Adherence to Exercise |
190 | — |
| SECONDARY Adherence to Nutrition |
80 | — |
| SECONDARY Adherence to Meditation |
71 | — |
| SECONDARY Adverse Events |
8 | — |
Summary
The purpose of this pilot study is to assess the feasibility of delivering a multicomponent prehabilitation and measuring patient-centered outcomes in older adults undergoing major surgery.
Eligibility Criteria
Inclusion Criteria
- Patient is scheduled to have a gastrointestinal, gynecological oncologic, urologic, and cardiovascular procedure
- Age 70 years+
- Age 65 years+ AND high risk per surgeon's clinical judgment
- Patient provides an informed e-consent or remote consent
Exclusion Criteria
- Surgery is scheduled less than 21 days
- Patient is considered an inappropriate candidate per the surgeon's assessment
- Non-English speaking
- Major cognitive impairment
- Patients with chronic kidney disease stage 3 or higher will be excluded from receiving protein supplement of the prehabilitation program
Data sourced from ClinicalTrials.gov (NCT05752474). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.