N/A
N=186
Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa
HIV/AIDS · Alcohol Abuse
Bottom Line
View on ClinicalTrials.gov: NCT05756790 ↗Enrolled (actual)
186
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Enrollment Rate — 31; 31; 30; 30 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Motivational Interviewing (Behavioral); Motivational Interviewing plus Breathalyzer (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of California, San Francisco
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Enrollment Rate |
31; 31; 30; 30; 29; 29 | — |
| PRIMARY Retention Rate |
30; 30; 29; 29; 29; 29 | — |
| SECONDARY Satisfaction With Intervention |
0; 0; 28; 28; 28; 27 | — |
| SECONDARY Mid-point Survey Completion |
30; 30; 28; 28; 29; 29 | — |
| SECONDARY Final Survey Completion |
30; 30; 29; 29; 29; 29 | — |
| SECONDARY Number of Participants Who Attended All Intervention Sessions |
0; 0; 25; 25; 26; 26 | — |
| SECONDARY 70% Breathalyzer Completion |
8 | — |
| SECONDARY Exploratory: ART Adherence |
0.61; .91; 0.70; .92; 0.58; .89 | — |
| SECONDARY Exploratory: Alcohol Use- Number of Drinking Days |
8.2; 5.7; 6.3; 5.8; 7.9; 8.0 | — |
| SECONDARY Exploratory: Alcohol Use- Score on AUDIT at 2 Months |
12.0; 10.43; 10.14; 11.11; 13.00; 11.38 | — |
| SECONDARY Exploratory: HIV Viral Load |
26; 28; 25 | — |
| SECONDARY Exploratory: Alcohol Use- Score on AUDIT at 6 Months |
7.83; 9.93; 8.80; 10.62; 8.27; 11.07 | — |
Summary
This project aims to develop and pilot test an intervention using couple-based motivational interviewing (MI) and mobile breathalyzers to reduce heavy alcohol use with couples living with HIV in South Africa.
Eligibility Criteria
Inclusion Criteria
- in a primary relationship for at least 6 months
- aged 18-49
- have at least one partner (the "index patient") with a positive AUDIT-C screen score
- has been on antiretroviral therapy (ART) for at least 6 months
- has disclosed HIV status to their partner
Exclusion Criteria
- Report severe intimate partner violence in the past 3 months and/or fear that their safety would be at risk (reported during screening)
Data sourced from ClinicalTrials.gov (NCT05756790). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.