N/A
N=30
Buoy Electrolyte Study on Hydration Status of Active Men and Women
Dehydration · Electrolyte Imbalance · Electrolyte Depletion · Fluid and Electrolyte Imbalance
Bottom Line
View on ClinicalTrials.gov: NCT05768789 ↗Enrolled (actual)
30
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Net Fluid Balance — 0.28; 0.05; 0.03 Liter
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Buoy Electrolyte (Dietary_supplement); Water only (Other); Nuun Electrolyte (Dietary_supplement)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Pittsburgh
- Primary completion
- Apr 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Net Fluid Balance |
0.28; 0.05; 0.03 | — |
| PRIMARY Electrolytes in Urine |
39; 58; 48 | — |
| PRIMARY Urine Osmolarity (mOsm/kg) |
1928; 1666; 1866 | — |
| SECONDARY Bio Impedance |
0.75; 0.64; 0.44 | — |
Summary
Buoy is an all-natural, organic, FDA compliant dietary electrolyte supplement that can be dissolved in 8-12oz water (or other liquid) and provide electrolytes in servings of 1/3 teaspoon. This study will evaluate Buoy in hydrating active adults.
Eligibility Criteria
Inclusion Criteria
- Male or female, >18 to 45 years of age
- Freely given written consent
- Non-tobacco users
- Negative pregnancy test in women of childbearing potential
- BMI 60 ml/min
- No known underlying medical condition
- Willing to refrain from EtOH for 24h prior to test day
- Willing to refrain from strenuous exercise for 24 h prior to each test day
- Acceptable to have one 8oz cup of coffee/liquid on the morning of the test, but must be consistent each visit
- Without active infection of any kind
- Engaged in exercise three or more hours per week
Exclusion Criteria
- Abnormal creatinine (Cr > 1.2).
- Proteinuria / hematuria / glucosuria based on urine dipstick.
- Diagnosed medical condition that would impede results (CHF, HTN, CAD, CKD, history of electrolyte abnormality).
- Pregnancy
- Use of diuretics within past 2 weeks
- Obesity (BMI > 35)
- Active infection based on symptoms (bacterial or viral)
- Hemodynamic abnormality at screening visit: Blood pressure less than 100/60 or greater than 140/90.
Data sourced from ClinicalTrials.gov (NCT05768789). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.