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N/A N=196 Randomized Single-blind Health Services Research

Implementing and Sustaining a Sleep Treatment to Improve Community Mental Health Part 2: Train-the-Trainer

Sleep Disorder · Circadian Dysregulation

Enrolled (actual)
196
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcome: Primary: Patient-level Outcome: Patient-Reported Outcomes Measurement Information System - Sleep DisturbanceMeasurement Information System - Sleep Disturbance — 66.67; 62.21; 60.54; 62.24 T-score — p=<0.001

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) (Behavioral); Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) (Behavioral); Usual Care Delayed Treatment (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of California, Berkeley
Primary completion
May 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Patient-level Outcome: Patient-Reported Outcomes Measurement Information System - Sleep DisturbanceMeasurement Information System - Sleep Disturbance
66.67; 62.21; 60.54; 62.24; 62.71; 62.05 <0.001 sig
PRIMARY
Provider-level Outcome: Acceptability Intervention Measure
SECONDARY
Patient-level Outcome: Patient-Reported Outcomes Measurement Information System - Sleep Related Impairment
63.12; 60.30; 59.24; 60.09; 60.59; 59.98 0.001 sig
SECONDARY
Patient-level Outcome: Composite Sleep Health Score
3.00; 2.25; 2.29; 2.45; 2.31; 2.43 0.09
SECONDARY
Patient-level Outcome: Sheehan Disability Scale
15.25; 12.49; 11.75; 11.88; 12.77; 11.86 0.002 sig
SECONDARY
Patient-level Outcome: The Diagnostic and Statistical Manual of Mental Disorders Cross-Cutting Symptom Measure
25.38; 23.48; 18.75; 23.25; 22.69; 23.68 0.002 sig
SECONDARY
Provider-level Outcome: Intervention Appropriateness Measure
5.00; 4.79; 4.82; 4.83; 4.56; 4.58
SECONDARY
Provider-level Outcome: Feasibility of Intervention Measure
4.95; 4.59; 4.64; 4.83; 4.60; 4.61

Summary

The train-the-trainer (TTT) approach is a promising method of sustaining training efforts in community mental health centers (CMHCs). This study will test the implementation and effectiveness outcomes of a sleep treatment delivered by CMHC providers who are trained and supervised within CMHCs via TTT. The investigators will test two versions of the sleep treatment, a "Standard" version and an "Adapted" version that has been adapted using theory, data and stakeholder inputs to improve the fit for SMI patients treated in community mental health centers.

Eligibility Criteria

Inclusion Criteria

The inclusion criteria for the CMHC local trainers are:

  • Employed in participating CMHCs
  • Completed a Generation 1 TranS-C training (i.e., led by UC Berkeley expert trainers)
  • Volunteer to participate and formally consent to participate

The inclusion criteria for CMHCs are:

  • Publicly funded adult mental health outpatient services
  • Support from CMHC leadership

The inclusion criteria for CMHC providers are:

  • Employed or able to deliver client-facing services to CMHC clients
  • Interest in learning and delivering TranS-C
  • Volunteer to participate and formally consent to participate

Consumers must meet the following inclusion criteria:

  • Aged 18 years and older
  • Meet criteria for an SMI per self-report and confirmed by referring provider or administration of the Mini International Neuropsychiatric Interview (MINI) (DSM-5, Version 7.0.0) by a licensed clinical social worker on the research team
  • Exhibit a sleep or circadian disturbance as determined by endorsing 4 "quite a bit" or 5 "very much" (or the equivalent for reverse scored items) on one or more PROMIS-SD questions
  • Receiving the standard of care for the SMI and consent to regular communications between the research team and provider
  • Consent to access their medical record and participate in assessments
  • Guaranteed place to sleep for at least 2 months that is not a shelter

Exclusion Criteria

  • Presence of an active and progressive physical illness or neurological degenerative disease directly related to the onset and course of the sleep and circadian dysfunction, or making participation in the study unfeasible based on confirmation from the treating clinician and/or medical record
  • Presence of substance abuse/dependence only if it makes participation in the study unfeasible
  • Current active intent or plan to commit suicide (those with suicidal ideation are eligible) only if it makes participation in the study unfeasible, or homicide risk
  • Night shift work >2 nights per week in the past 3 months
  • Pregnancy or breast-feeding
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05805657). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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