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N/A N=394 Randomized Single-blind Other

McGrath Videolaryngoscopy and Direct Laryngoscopy Rapid Sequence Intubation

Surgery

Enrolled (actual)
394
Serious AEs
0.0%
Results posted
Feb 2025
Primary outcome: Primary: Visualization of the Vocal Cords — 90; 85; 63; 67 Participants — p=0.26

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
McGrath videolaryngoscope for rapid sequence endotracheal intubation (Device); Conventional direct laryngoscopy using a Macintosh blade (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
The Cleveland Clinic
Primary completion
Jun 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Visualization of the Vocal Cords
90; 85; 63; 67; 26; 28 0.26
SECONDARY
Number of Participants With 1, 2, 3, and 4 Intubation Attempts
167; 176; 21; 21; 0; 1 0.86
SECONDARY
Intubation Failure.
3; 1 0.36

Summary

The study seeks to compare the efficacy of conventional direct laryngoscopy using a Macintosh blade with the McGrath videolaryngoscope for rapid sequence endotracheal intubation.

Eligibility Criteria

Inclusion Criteria

  • Elective surgery requiring oral endotracheal intubation for general anesthesia;
  • Anticipated extubation in the operating room;
  • American Society of Anesthesiologists (ASA) physical status 2-3;
  • Age between 18 and 99 years;
  • Body Mass index ≥ 40 kg/m2.

Exclusion Criteria

  • Refusal of participation by attending anesthesiologist;
  • Indicated rapid sequence induction for any reason including, but not limited to high risk of aspiration
  • Indicated fiberoptic awake intubation.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05850052). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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