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N/A N=151 Randomized Treatment

A Skin Glue Versus Subcuticular Suture for Cesarean Closure Study

Cesarean Section · Complication · Wound

Enrolled (actual)
151
Serious AEs
10.6%
Results posted
Jan 2026
Primary outcome: Primary: Patient Scar Satisfaction Scale Score — 13; 13.5 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Dermabond Prineo (Device); Suture (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Columbia University
Primary completion
Dec 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Patient Scar Satisfaction Scale Score
13; 13.5
SECONDARY
Incidence of Surgical Site Infection (SSI)
2; 2; 7; 6
SECONDARY
Skin Closure Time
8.0; 9.0
SECONDARY
Operative Time
65.5; 64.5

Summary

The aim of this study is to compare cesarean incision outcomes between patients with incision closed with the Dermabond Prineo system compared to standard subcuticular suture.

Eligibility Criteria

Inclusion Criteria

  • Women age 18 years or older
  • All women scheduled for primary or repeat cesarean deliveries
  • All women undergoing intrapartum or antepartum cesarean delivery
  • Pfannenstiel skin incision
  • Birth of a live infant at time of cesarean delivery

Exclusion Criteria

  • Vertical skin incision
  • Cesarean hysterectomy
  • Emergency or stat cesarean delivery excluding standard preoperative preparation measures (i.e., use of Chlorhexidine skin prep, vaginal prep, etc)
  • Intrapartum stillbirth
  • Planned postpartum follow up at another facility
  • Contraindications to routine postpartum pain medications
  • Adhesive or tape allergy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05903547). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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