N/A
Completed N=155
mHealth for Young Adult Cancer Survivors
Survivorship · Cancer · psychological well-being
Source: ClinicalTrials.gov NCT05905250 ↗
Enrolled (actual)
155
Serious AEs
0.0%
Results posted
Dec 2025
Primary outcomePrimary: Retention — 74; 72 Participants
Summary
We aim to refine and pilot test an 8-week phone- and app-based intervention to promote hope, and thereby mitigate life disruption caused by cancer diagnosis and treatment, among young adults (YAs); our proposal involves (Aim 1) formative research among YA survivors and healthcare providers; and (Aim 2) an randomized controlled trial (RCT) of the intervention vs. attention control among 150 YA cancer survivors. The proposed research is innovative in its use of: 1) a novel intervention target - hope - as a mechanism for addressing goal-disruption and quality of life (QOL) among YA survivors; and 2) novel mHealth components and population-based recruitment strategy (via social media) that are particularly relevant to YA survivors and those with potentially limited access to healthcare. This proposal has potential high impact due to the number of YA cancer survivors for whom the intervention may be relevant, the intervention's potential utility in enhancing hope and QOL among YAs, and its reach/scalability.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Retention |
75; 72 | — |
| PRIMARY Adherence |
7.0; 7.3 | — |
| PRIMARY Acceptability |
67; 60 | — |
| PRIMARY Hope |
50.78; 49.82 | — |
| SECONDARY Hope |
50.78; 49.82 | — |
| SECONDARY Quality of Life - Patient-Reported Outcome Measurement Information System (PROMIS) Global Health Scale |
51.17; 51.56 | — |
| SECONDARY Functional Assessment of Cancer Therapy - General (FACT-G) |
79.18; 79.15 | — |
| SECONDARY Depression and Anxiety Symptoms - Mean Patient Reported Outcome Measures for Anxiety and Depression Subscales (2-month) |
53.62; 52.68 | — |
| SECONDARY Depression and Anxiety Symptoms - Mean Patient Reported Outcome Measures for Anxiety and Depression Subscales (4-month) |
52.05; 53.04 | — |
Eligibility Criteria
Inclusion Criteria
- Diagnosis of stage I-IV cancer from age 18-39
- Completion of curative treatment (surgery, chemotherapy and/or radiation) within three years of study enrollment
- No significant psychological disabilities
- Able to complete forms and understand instructions in English
- Smartphone access
- Aim 2: Able to commit to 8-week remotely delivered study
Exclusion Criteria
- Completion of curative treatment (surgery, chemotherapy and/or radiation) over three years ago or currently in treatment
- Significant psychological disabilities
Data sourced from ClinicalTrials.gov (NCT05905250). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.