N/A
Completed N=18
Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living
Source: ClinicalTrials.gov NCT05956665 ↗Enrolled (actual)
18
Serious AEs
16.7%
Results posted
Oct 2025
Primary outcomePrimary: Total Number of Medications That Have Been Deprescribed Since Enrollment — 4 Medications
Summary
This single-arm pilot study will evaluate the effects of an intervention to reduce exposure to unnecessary or potentially harmful medications among residents with dementia living in an assisted living facility. The goal of the intervention is to safely deprescribe medications (defined by dose reductions and stopped medications), based on a combination of clinical criteria and resident/surrogate preferences. The investigators will evaluate the effects of the intervention on the total number of medications deprescribed from enrollment at 30, 60, and 90 days along with resident/surrogate reports of quality of life at enrollment and 90 days.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Total Number of Medications That Have Been Deprescribed Since Enrollment |
4 | — |
| PRIMARY Resident Quality of Life |
104.5 | — |
Eligibility Criteria
Inclusion Criteria
- Resident of assisted living facility
- Speaks English (due to interview-based assessments)
- Diagnosis of dementia
- Taking a total of 5 medications or at least one potentially inappropriate medication (defined by the Beers criteria, STOPP criteria, and the Rationalization of home medication by an Adjusted STOPP in older Patients [RASP])
- Able self-consent or has a proxy (surrogate)
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT05956665). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.