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N/A N=120 Diagnostic

Evaluation of Physiological Variables and Detection of Blood Loss in Healthy Adults With Different Subject Positioning by the CM-1500

Fluid Loss · Blood Loss

Enrolled (actual)
120
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Impact of Subject Positioning on Percent Change of Heart Rate (HR) After Minor Blood Loss (e.g., 500mL) — 10.7; 14.7 percent change

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Whole blood donation supine (Device); Whole blood donation reclined (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Zynex Monitoring Solutions
Primary completion
Apr 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Impact of Subject Positioning on Percent Change of Heart Rate (HR) After Minor Blood Loss (e.g., 500mL)
10.7; 14.7

Summary

The study is a prospective, non-randomized, non-blinded, non-significant risk study enrolling up to 60 healthy adult subjects consented to undergo a 1-unit whole blood draw procedure. Subjects will wear the study device (CM-1500) while positioned in either a supine or reclined position during the blood draw and study-required physiological parameters will be captured pre-, during, and post-donation.

Eligibility Criteria

Inclusion Criteria

  • Ability to provide written informed consent
  • Ability and willingness to comply with the study procedures and duration requirements
  • 18 years of age or older
  • Consented and eligible to undergo a single unit whole blood donation

Exclusion Criteria

  • Females who are pregnant or breastfeeding
  • Undergone an amputation of any upper extremity
  • Diagnosed with dextrocardia
  • Subjects who have a pacemaker
  • Subjects with body hair density which prevents adequate application of device electrodes
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05980013). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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