N/A N=25 Supportive Care

Living With Multimorbidity: CO-ORDINATE Program

Multimorbidity · Quality of Life · Symptom Management

Bottom Line

View on ClinicalTrials.gov: NCT05985044 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jan 2025

Primary outcome: Primary: Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Pain — 5; 4; 5 score on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Care cO-ORDInatioN And sympTom managEment (CO-ORDINATE) Intervention (Other)
Age: Adult, Older Adult · 55+ yrs
Sex: All
Sponsor: Johns Hopkins University
Primary completion: Mar 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Pain	5; 4; 5	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Tiredness	3; 3; 6	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Drowsiness	2; 3; 5	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Nausea	0; 0; 1	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Lack of Appetite	0; 1; 3.3	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Shortness of Breath	0; 3; 5	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Depression	0; 3; 4.5	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Anxiety	0; 2; 2.5	—
PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Well-being	5; 4; 3.3	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Physical Functioning	50; 40; 32.5	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Role Physical	25; 0; 0	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Role Emotional	33.33; 33.33; 16.67	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Vitality	45; 50; 52.5	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Mental Health	68; 68; 76	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Social Functioning	50; 62.5; 50	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Bodily Pain	38.75; 57.5; 50	—
PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - General Health	50; 45; 40	—
SECONDARY Health-care Utilization - Total Healthcare Utilization	1; 1	—
SECONDARY Health-care Utilization - Emergency Department (ED) Visit s	1; 1	—
SECONDARY Health-care Utilization - Hospitalization	1; 0	—
SECONDARY Health-care Utilization - Critical Care Admission	1; 0	—

Summary

Multimorbidity is common and is the coexistence of two or more chronic conditions in the same individual. People with multimorbidity suffer from a high symptom burden, directly affecting quality of life (QOL). Hospitalization can be a window of opportunity to initiate interventions to promote recovery and resilience and enhance QOL. However, interventions targeting the symptom trajectory and burden of patients with multimorbidity are lacking. Thus, the investigators envisage a nurse-led pre-discharge intervention augmented by telephone support, focusing on care coordination and symptom management. This approach is anticipated to help reduce symptom burden and improve QOL.

Eligibility Criteria

Inclusion Criteria

English speakers who are planned for discharge from Johns Hopkins Hospital (JHH) IMCU
Who meet the criteria for being admitted to IMCU and planned discharge with multimorbidity as defined by two or more chronic conditions.

Exclusion Criteria

Who can not provide informed consent or have documented cognitive impairment

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT05985044). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.