N/A
Completed N=25
Living With Multimorbidity: CO-ORDINATE Program
Multimorbidity · quality of life · Symptom Management
Source: ClinicalTrials.gov NCT05985044 ↗
Enrolled (actual)
25
Serious AEs
0.0%
Results posted
Jan 2025
Primary outcomePrimary: Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Pain — 5; 4; 5 score on a scale
Summary
Multimorbidity is common and is the coexistence of two or more chronic conditions in the same individual. People with multimorbidity suffer from a high symptom burden, directly affecting quality of life (QOL). Hospitalization can be a window of opportunity to initiate interventions to promote recovery and resilience and enhance QOL. However, interventions targeting the symptom trajectory and burden of patients with multimorbidity are lacking. Thus, the investigators envisage a nurse-led pre-discharge intervention augmented by telephone support, focusing on care coordination and symptom management. This approach is anticipated to help reduce symptom burden and improve QOL.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Pain |
5; 4; 5 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Tiredness |
3; 3; 6 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Drowsiness |
2; 3; 5 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Nausea |
0; 0; 1 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Lack of Appetite |
0; 1; 3.3 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Shortness of Breath |
0; 3; 5 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Depression |
0; 3; 4.5 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Anxiety |
0; 2; 2.5 | — |
| PRIMARY Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Well-being |
5; 4; 3.3 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Physical Functioning |
50; 40; 32.5 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Role Physical |
25; 0; 0 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Role Emotional |
33.33; 33.33; 16.67 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Vitality |
45; 50; 52.5 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Mental Health |
68; 68; 76 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Social Functioning |
50; 62.5; 50 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - Bodily Pain |
38.75; 57.5; 50 | — |
| PRIMARY Quality of Life Assessed by Short Form Survey (SF-36) Score - General Health |
50; 45; 40 | — |
| SECONDARY Health-care Utilization - Total Healthcare Utilization |
1; 1 | — |
| SECONDARY Health-care Utilization - Emergency Department (ED) Visit s |
1; 1 | — |
| SECONDARY Health-care Utilization - Hospitalization |
1; 0 | — |
| SECONDARY Health-care Utilization - Critical Care Admission |
1; 0 | — |
Eligibility Criteria
Inclusion Criteria
- English speakers who are planned for discharge from Johns Hopkins Hospital (JHH) IMCU
- Who meet the criteria for being admitted to IMCU and planned discharge with multimorbidity as defined by two or more chronic conditions.
Exclusion Criteria
- Who can not provide informed consent or have documented cognitive impairment
Data sourced from ClinicalTrials.gov (NCT05985044). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.