N/A N=25 Living With Multimorbidity: CO-ORDINATE Program
Multimorbidity · Quality of Life · Symptom Management
Primary: Symptom Burden Assessed by Edmonton Symptom Assessment System (ESAS) Score - Pain — 5; 4; 5 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=13,182 Comorbidities and Outcomes in Early Rheumatoid Arthritis
Rheumatoid Arthritis
Primary: Event Rate for a Cardiovascular Composite of Incident Myocardial Infarction, Stroke, or Heart Failure — 10.62; 8.13 Events per 1000 person years
N/A N=264 Patient Priority Care for Older Adults With Multiple Chronic Conditions
Multiple Chronic Conditions
Primary: Treatment Burden — 11.9; 11.6; 12.7; 17.9 score on a scale
N/A N=344 Multiple Chronic Conditions for Older Adults
Chronic Disease
Primary: PROMIS Global Health Measure Score — 46.27; 46.21; 44.92; 46.38 T-score
N/A N=1,400 Integrated Care (IC) Models for Patient-Centered Outcomes
Diabetes · Asthma · Chronic Obstructive Pulmonary Disease
Primary: Patient Activation — 61.87; 63.73; 63.82; 63.15 score on a scale — p=0.0211
N/A N=312 Clinical Trials for Elderly Patients With Multiple Disease
Chronic Obstructive Pulmonary Disease (COPD) · Congestive Heart Failure (CHF) · Sleep Disordered Breathing (SDB)
Primary: Time to First Hospitalization — 255; 224 days — p=0.342
N/A N=266,499 Polypharmacy and Outcomes After Elective Noncardiac Surgery
Polypharmacy · Surgical Procedure, Operative · Morality
Primary: Mortality — 4356; 1919 Participants
N/A N=21 Psoriasis Inflammation and Systemic Co Morbidities
Psoriasis
Primary: Change in Histology
N/A N=828 Multiple Areas of Pain (MAP)
Chronic Pain
Primary: Multi-site Pain Index — 0.52 units on a scale
N/A N=19 The Adverse Drug Reaction (ADRe) Profile for Polypharmacy
Polypharmacy
Primary: Number of Participants With Changes in Signs and Symptoms Related to Adverse Effects of Prescribed Medicines. Clinical Gains and Benefits to Residents — 17 Participants
N/A N=268 ElderTree Smart System for Older Adults
Chronic Pain
Primary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Short Form v2.1 - Pain Interference Score — 58.44; 59.57; 59.19; 57.94 score on a scale
N/A N=327 Morbidity in Newly Diagnosed type2 Diabetes in Adults
Type2 Diabetes Mellitus · Complications
Primary: Number and Prevalence of Patients With Diabetic Retinopathy — 9; 18 Participants — p=0.706
N/A N=310 A Retrospective Observational Study to Assess the Impact of Co-morbidities on Treatment Response in Inflammatory Bowel Disease
Inflammatory Bowel Disease
Primary: Impact of the Comorbidities Profile in Inflammatory Bowel Disease (IBD) Participants on Lack of Treatment Response to Biological Therapy — 0.59; 2.16; 2.67 odds ratio…
N/A N=22 Shared Decision Making About Medication Use for People With Multiple Health Problems
Polypharmacy · Dementia · Multiple Chronic Conditions
Primary: Preliminary Efficacy of the Intervention to be Assessed From Primary Care Clinician's Intervention Visit Clinical Notes and EHR — 15; 7; 7; 7 Participants
N/A N=21 Patient Priorities Care for Hispanics With Dementia
Multiple Chronic Conditions · Dementia
Primary: Self-reported Perceived Value of Patient Priorities Care (PPC) Approach — 75; 85.7 percentage of participants
N/A N=2,000 Morbidity, Mortality And Risk Factors of Mpox in HIV Negative High Risk Sexual Health Clinic Attenders and People Living With HIV
Monkeypox · HIV Coinfection
Primary: Severe Mpox Lesions — 6; 2 participants — p=0.097
N/A N=23 Medication Adherence With Polyglot Meducation
Hypertension · Diabetes · Hypercholesterolemia
Primary: Medication Possession Ratio at Baseline — 65.0 percentage of medication possession
N/A N=1,206 Epidemiology of Depression, Anxiety, and Cognitive Impairment
Depression · Anxiety · Cognitive Impairment
Primary: Participants With Depression by Patient Health Questionnaire - 9 — 177 participants
N/A N=95,055 Healthcare Resource Utilisation, Common Mental Health Problems, and Infections in People With Inflammatory Bowel Disease
Inflammatory Bowel Diseases · Ulcerative Colitis · Crohn Disease
Primary: Prevalence of Anxiety Episodes (Crohn's Disease) — 262; 892 Participants
N/A N=238 Implementing Health Plan-Level Care Management for Solo & Small Practices
Bipolar Disorder · Depression
Primary: Health-related Quality of Life, as Measured by the Mental Health Component Score — 38.2; 43.2 score on a scale
N/A N=635 A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
Posttraumatic Stress Disorder · Depression · Alcohol-Related Disorders
Primary: Change From Baseline PTSD Checklist- Civilian (PCL-C) Over the Course of the Year After Injury — -1.65; 0.08; -4.02; -1.44 score on a scale
N/A N=44 Cirrhosis Medical Home
Cirrhosis, Liver
Primary: Enrollment Rate — 20; 20 Participants
N/A N=4,322 Care Coordination for Complex Cancer Survivors in an Integrated Safety Net System
Breast Cancer · Colorectal Cancer
Primary: Proportion of Complex Cancer Survivors Meeting Quality of Care Guidelines for Chronic Conditions and Follow-up Cancer Surveillance
N/A N=294 Comprehensive vs. Assisted Management of Mood and Pain Symptoms
Pain · Depression · Anxiety
Primary: Composite Z-score of Pain-anxiety-depression Severity — -0.52; -0.65 units on a scale
N/A N=14 Chronic Kidney Disease Among Frail Elderly
Chronic Kidney Disease
Primary: Mortality — 0; 0 percentage of mortality
N/A N=554 Communicating Multiple Disease Risks: A Translation of Risk Prediction Science
Healthy Volunteers
Primary: Change From Baseline to 90-day Follow-up in Self Reported Weekly Minutes of Exercise — 92.2; 37.5; 63.1; 60.0 minutes — p=0.0288
N/A N=331 PACT for Individuals With Serious Mental Illness
Schizophrenia Spectrum & Other Psychotic Disorders
Primary: Provision of Appropriate Preventive and Medical Treatments — 144; 117; 146; 131 Participants
N/A N=25,507 Minnesota Care Coordination Effectiveness Study
Chronic Disease · Multi-morbidity · Care Coordination
Primary: Change in Composite Measure of Care Quality — 7.0; 4.5; 5.9; 5.9 Change in percent — p=0.19
N/A N=97 Multifactorial Treatment of Cardiovascular Risk in Diabetic Patients: Identification of Treatment Non-Responders
Diabetes Mellitus, Type II
Primary: Change of Intima Media Thickness (IMT) — -0.023 mm — p=0.021
Phase 1 N=32 Effects Multimodal Mind and Body Approach for MCI
Mild Cognitive Impairment
Primary: Retention — 11; 15 Participants