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Phase 4 Completed N=61 Randomized Single-blind Treatment

Optimal Blood Pressure Treatment Thresholds Postpartum

Hypertensive Disorder of Pregnancy · Pre-eclampsia · Hypertension · Eclampsia
Source: ClinicalTrials.gov NCT06069102 ↗
Enrolled (actual)
61
Serious AEs
0.0%
Results posted
Jun 2026
Primary outcomePrimary: Percent of Participants Eligible, Enrolled and Retained (Feasibility) — 61 Participants
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

The objective of this research project is to conduct a single-site pilot trial within our institution's clinical remote blood pressures (BP) management program to assess the feasibility and effect of tight blood pressure control versus usual care in the immediate postpartum period after a hypertensive disorder of pregnancy (HDP). The investigators' central hypothesis is that tight blood pressure control will be feasible and acceptable to postpartum individuals and will result in lower BP at six months postpartum and a reduction in postpartum hospital readmissions. Subjects will undergo 3 study visits (1 in-person and 2 remote) involving BP measurements, blood draws, and/or questionnaires. Up to 60 adult subjects will be enrolled at Magee-Women's Hospital.

Outcome Measures

OutcomeResultp-value
PRIMARY
Percent of Participants Eligible, Enrolled and Retained (Feasibility)
61
SECONDARY
Number of Participants With Anti-hypertensive Medication Use
5; 1
SECONDARY
Anti-hypertensive Medication Use
4; 5
SECONDARY
Mean Arterial Pressure (Efficacy)
92.1; 91.7
SECONDARY
Mean Arterial Pressure
97.0; 89.5
SECONDARY
Systolic Blood Pressure
120.4; 116.5
SECONDARY
Diastolic Blood Pressure
83.8; 76.6
SECONDARY
Change in MAP
-4.1; -8.4
SECONDARY
Change in Systolic BP
-6.5; -10.0
SECONDARY
Change in Diastolic BP
-3.0; -7.7
SECONDARY
Number of Participants With Hospital Readmissions
0; 0
SECONDARY
Number of Participants With ER Visits
2; 1

Eligibility Criteria

Inclusion Criteria

  • Postpartum individuals ≥18 years old
  • Preeclampsia or gestational hypertension diagnosis (complying ACOG criteria)
  • Enrolled in remote BP management program.

Exclusion Criteria

  • Pre-pregnancy hypertension
  • Pre-pregnancy diabetes
  • Maternal cardiac disease
  • Chronic kidney disease
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06069102). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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