Phase 4
N=61
Optimal Blood Pressure Treatment Thresholds Postpartum
Hypertensive Disorder of Pregnancy · Pre-Eclampsia · Hypertension · Eclampsia · Gestational Hypertension
Bottom Line
View on ClinicalTrials.gov: NCT06069102 ↗Enrolled (actual)
61
Serious AEs
0.0%
Results posted
Jun 2026
Primary outcome: Primary: Percent of Participants Eligible, Enrolled and Retained (Feasibility) — 61 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Usual care (Drug); Tight blood pressure control (Drug)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Alisse Hauspurg
- Primary completion
- May 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percent of Participants Eligible, Enrolled and Retained (Feasibility) |
61 | — |
| SECONDARY Number of Participants With Anti-hypertensive Medication Use |
5; 1 | — |
| SECONDARY Anti-hypertensive Medication Use |
4; 5 | — |
| SECONDARY Mean Arterial Pressure (Efficacy) |
92.1; 91.7 | — |
| SECONDARY Mean Arterial Pressure |
97.0; 89.5 | — |
| SECONDARY Systolic Blood Pressure |
120.4; 116.5 | — |
| SECONDARY Diastolic Blood Pressure |
83.8; 76.6 | — |
| SECONDARY Diastolic Blood Pressure |
83.8; 76.6 | — |
| SECONDARY Change in MAP |
-4.1; -8.4 | — |
| SECONDARY Change in Systolic BP |
-6.5; -10.0 | — |
| SECONDARY Change in Diastolic BP |
-3.0; -7.7 | — |
| SECONDARY Number of Participants With Hospital Readmissions |
0; 0 | — |
| SECONDARY Number of Participants With ER Visits |
2; 1 | — |
Summary
The objective of this research project is to conduct a single-site pilot trial within our institution's clinical remote blood pressures (BP) management program to assess the feasibility and effect of tight blood pressure control versus usual care in the immediate postpartum period after a hypertensive disorder of pregnancy (HDP).
The investigators' central hypothesis is that tight blood pressure control will be feasible and acceptable to postpartum individuals and will result in lower BP at six months postpartum and a reduction in postpartum hospital readmissions. Subjects will undergo 3 study visits (1 in-person and 2 remote) involving BP measurements, blood draws, and/or questionnaires. Up to 60 adult subjects will be enrolled at Magee-Women's Hospital.
Eligibility Criteria
Inclusion Criteria
- Postpartum individuals ≥18 years old
- Preeclampsia or gestational hypertension diagnosis (complying ACOG criteria)
- Enrolled in remote BP management program.
Exclusion Criteria
- Pre-pregnancy hypertension
- Pre-pregnancy diabetes
- Maternal cardiac disease
- Chronic kidney disease
Data sourced from ClinicalTrials.gov (NCT06069102). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.