N/A
Completed N=1,113
Renal Replacement Therapy and In-Hospital Mortality Incidence in Cardiac Surgery Associated Acute Kidney Injury
Source: ClinicalTrials.gov NCT06091982 ↗Enrolled (actual)
1,113
Serious AEs
13.5%
Results posted
Oct 2024
Primary outcomePrimary: Mortality — 96; 34 Participants — p=<0.0001
Summary
The goal of this study is to analyse the relation of severe acute kidney injury post cardiac surgery which characterised by the need of renal replacement therapy, with in-hospital postoperative mortality incidence.
The main question it aims to answer:
To compare between patients complicated with acute kidney injury and exposure of renal replacement therapy (AKI-RRT) and patients complicated with acute kidney injury which does not require renal replacement therapy, in associated with in-hospital postoperative mortality.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mortality |
96; 34 | <0.0001 sig |
| SECONDARY ICU Stay Over 5 Days |
183; 89 | <0.0001 sig |
| SECONDARY Mechanical Ventilation > 48 Hours |
198; 88 | <0.0001 sig |
Eligibility Criteria
Inclusion Criteria
- Patients who are at least 18 years old, underwent cardiac surgery in Harapan Kita National Cardiovascular Center from January 2020 to December 2022.
- Patients with condition was complicated with Acute Kidney Injury (AKI) which was characterised by an increase in serum creatinine > 0.3 mg/dL or > 150% of the preoperative serum creatinine value, which was checked within 12 hours post-operative.
- All patients' data is recorded in the medical records unit.
Exclusion Criteria
- Patients with previous history of dialysis or renal failure in dialysis.
- Incomplete or loss of patients' data.
Data sourced from ClinicalTrials.gov (NCT06091982). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.