N/A
N=1,113
Renal Replacement Therapy and In-Hospital Mortality Incidence in Cardiac Surgery Associated Acute Kidney Injury
Acute Kidney Injury
Bottom Line
View on ClinicalTrials.gov: NCT06091982 ↗Enrolled (actual)
1,113
Serious AEs
13.5%
Results posted
Oct 2024
Primary outcome: Primary: Mortality — 96; 34 Participants — p=<0.0001
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Renal Replacement Therapy (RRT) (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
- Primary completion
- Jun 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mortality |
96; 34 | <0.0001 sig |
| SECONDARY ICU Stay Over 5 Days |
183; 89 | <0.0001 sig |
| SECONDARY Mechanical Ventilation > 48 Hours |
198; 88 | <0.0001 sig |
Summary
The goal of this study is to analyse the relation of severe acute kidney injury post cardiac surgery which characterised by the need of renal replacement therapy, with in-hospital postoperative mortality incidence.
The main question it aims to answer:
To compare between patients complicated with acute kidney injury and exposure of renal replacement therapy (AKI-RRT) and patients complicated with acute kidney injury which does not require renal replacement therapy, in associated with in-hospital postoperative mortality.
Eligibility Criteria
Inclusion Criteria
- Patients who are at least 18 years old, underwent cardiac surgery in Harapan Kita National Cardiovascular Center from January 2020 to December 2022.
- Patients with condition was complicated with Acute Kidney Injury (AKI) which was characterised by an increase in serum creatinine > 0.3 mg/dL or > 150% of the preoperative serum creatinine value, which was checked within 12 hours post-operative.
- All patients' data is recorded in the medical records unit.
Exclusion Criteria
- Patients with previous history of dialysis or renal failure in dialysis.
- Incomplete or loss of patients' data.
Data sourced from ClinicalTrials.gov (NCT06091982). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.