N/A
Completed N=178
Feasibility Trial Using an Inpatient Insulin Dosing Calculator
Source: ClinicalTrials.gov NCT06206525 ↗Enrolled (actual)
178
Serious AEs
0.0%
Results posted
Apr 2026
Primary outcomePrimary: Clinical Significant Hypoglycemia — 0; 1 Participants — p=0.6
Summary
The goal of this feasibility trial is to test whether a novel insulin dosing calculator can improve blood glucose management for patients with type 2 diabetes mellitus on hospital admission. The main questions it aims to answer are:
* Whether using this calculator leads to no excessive hypoglycemia?
* Whether using this calculator leads to a decrease of hyperglycemia?
Participants will receive initial insulin doses by the calculator on hospital admission, and the rest of care will follow standard of care. Participants will be compared with patients in the UW observational cohort who received initial insulin doses by standard of care.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Clinical Significant Hypoglycemia |
0; 1 | 0.6 |
| SECONDARY Mean Blood Glucose Concentration (mg/dL) |
184.5; 204.0 | 0.023 sig |
| SECONDARY Clinical Significant Hyperglycemia |
1; 42 | 0.0005 sig |
| SECONDARY Hypoglycemia Lower Than 70 mg/dL |
0; 2 | 0.5 |
Eligibility Criteria
Inclusion Criteria
- Patients who are admitted to University of Washington Medical Centers
- With history of type 2 and/or steroid-induced diabetes mellitus
- Receiving insulin therapy prior to admission
Exclusion Criteria
- Patients who are admitted to ICU or obstetrics ward
- Patients who are admitted for elective surgery or procedure
- Patients who present with diabetic ketone acidosis, hyperosmolar hyperglycemic state or require intravenous insulin infusion
- Patients who have no meal intake for 24 hours prior to admission, or planned nothing per oral (NPO) during the first 24 hours after admission
- Patients who report low appetite (25% or less) on admission or have a significantly decreased level of consciousness that study team does not think they are going to eat right after admission
- Patients who receive enteral feeding after admission
- Patients who develop severe acute kidney injury needing dialysis therapy
Data sourced from ClinicalTrials.gov (NCT06206525). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.