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N/A N=178 Randomized Single-blind Treatment

The Effects of Executive Functions and Social Cognition on Mental Health

Autism or Autistic Traits · Mental Health Disorder · Executive Dysfunction · Social Cognition

Enrolled (actual)
178
Serious AEs
Results posted
Mar 2025
Primary outcome: Primary: Depression_1 — 9.87; 10.24; 7.65; 9.15 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
MindZone (Other)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Ibn Haldun University
Primary completion
Oct 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Depression_1
9.87; 10.24; 7.65; 9.15
PRIMARY
Anxiety
9.42; 9.44; 6.74; 8.03
PRIMARY
Stress
7.61; 6.32; 5.58; 7.79
PRIMARY
Cognitive Flexibility - Errors Rate
21; 22; 40; 37
PRIMARY
Working Memory - Errors Rate
20.65; 15.09; 13.13; 10.50
PRIMARY
Inhibition - Errors Rate
5.48; 3.24; 4.48; 3.85
SECONDARY
Cognitive Empathy
24.45; 25.65; 25.39; 26.59
SECONDARY
Self-Assessment Manikin for Affective Empathy
130.16; 119.35; 126.16; 117.38

Summary

The objective of this study is to analyze the effects of executive functions (EFs) and social-cognitive abilities on the associations between autistic traits and mental health indicators (depression, anxiety, and stress). Moreover, the study will produce online training modules for executive functions and social cognition, aimed at reducing the likelihood of adverse mental health outcomes in individuals with and without elevated autistic traits. Therefore, four main hypotheses will be addressed: 1. Revealing the mediating role of executive functions (cognitive flexibility, inhibitory control, and working memory) will help predict the association between autistic traits and mental health symptoms (anxiety, depression, and stress). 2. Revealing the mediating role of social cognitive skills (cognitive empathy and affective empathy) will help predict the association between autistic traits and mental health symptoms (anxiety, depression, and stress). 3. Online training in executive functions and social cognitive skills will help develop executive functions (working memory, inhibitory control, and cognitive flexibility) and social cognitive skills (cognitive empathy and affective empathy) in the current sample. 4. Online training in executive functions and social cognitive skills will promote mental health by reducing distress, depression, and anxiety symptoms in the current sample. Participants will be between the ages of 18-35 because previous findings indicate that the age of onset of various mental health problems is between the ages of 17 and 35. Participants will be randomly assigned to the experimental and control groups. Using a longitudinal design including pre-test, post-test, and follow-up conditions to test the effectiveness of combined EFs and social cognition online training for mental health symptoms.

Eligibility Criteria

Inclusion Criteria

  • aged 18 or above
  • Fluent in writing and speaking in Turkish
  • No record of any psychiatric disorders
  • No record of neurological conditions

Exclusion Criteria

  • under age 18
  • Have any record of psychiatric
  • Have any neurological conditions
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06213194). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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