Clinical Trial Search

Primary: Total Brain Volume — 1634.1; 1409.8; 1236.7; 1401.9 cubic centimeters

Primary: Pediatric Anxiety Rating Scale (Measures the Severity of Anxiety Symptoms) — 16.33; 17.62; 11.58; 16.05 units on a scale

Primary: Change in Score on Conners Adults Attention Deficit Hyperactivity Disorder (ADHD) Rating Scale — 68.6; 71.8; 53.4; 57 T-score

Primary: Pediatric Anxiety Rating Scale. — 11.62; 14.04 units on a scale — p=.04

Primary: Change in Responses to Affective Touch — 3.01; 4.06 units on a scale

Primary: Developmental Neuropsychological Assessment (NEPSY) Memory for Faces Delayed

Primary: Percent Change of ABC - Irritability Subscale Score — -44.5 percent change in scores

Primary: Reduction in Social Responsiveness Scale, Second Edition (SRS-2) - Adult (Relative/Other Report) — 68.67; 70.41; 66.08; 72.33 Scaled Score — p=.006

Primary: Change From Baseline in the Pervasive Developmental Disorder-Behavioral Inventory (PDDBI) - Autism Composite Score — -4.5; -6.4 units on a scale — p=0.5

Primary: Change From Baseline in Attention Deficit Hyperactivity Disorder Symptom Checklist (ADHD-SCL) — -8.5 change in scale score

Primary: Change From Screening/Baseline in Social Responsiveness Scale (SRS) at 4 Weeks, 10 Weeks, 18 Weeks and 22 Weeks — -7.79; -14.76; -1.38; -14.48 units on a scale

Primary: Change From Baseline in Parent Rated Social Responsiveness Scale (SRS) Scores During Treatment. — 9.73; 3.18 units on a scale — p=0.0275

Primary: Number of Participants With Improvement on the Clinical Global Impression-Improvement (CGI-I) Scale — 3; 1 Participants

Primary: Clinical Global Impressions-Improvement — 1.8 units on a scale

Primary: Change From Baseline in Aberrant Behavior Checklist-Irritability at 12 Weeks — 7.6; -0.6 units on a scale

Primary: Reading the Mind in the Eyes Task (RMET) — 18.07; 18.08; 17.86; 18.09 total raw score

Primary: Change in Severity of Adolescent Depressive Symptoms, Self-report — 8.14 T-score

Primary: Resting State Functional Connectivity (rsFC) Salience Network (Anterior Cingulate Cortex (ACC) and Insula Versus Visual Cortex) — 0.338; 0.400; 0.428; 0.522 z-scores…

Primary: Change From Baseline in Anxiety Severity on the Pediatric Anxiety Rating Scale After 16 Weeks of Treatment. — 3.43; 3.47; 3.28; 2.13 units on a scale

Primary: Mean Conners' Teacher ADHD Index T Score by Dose — 72.8; 63.1; 63.6; 61.5 Units on a scale (T-scores) — p==.001

Primary: Change Task - Stop Signal Reaction Time — 233.8; 238.3; 213.6; 234.7 miliseconds — p=0.36

Primary: Change in ASD Symptoms Social Responsiveness Scales 2 (SRS-2) Scales From Baseline to Week 8 — -32.4 scores on a scale

Primary: Child Externalizing Behavior Problems as Evidenced by Reductions in the Externalizing Scores on a Standardized Parent-report Questionnaire. — 68.40; 66.49 t-scores

Primary: Change in Incidental Face Memory — 0.6588; -0.1604; 0.469; -0.77 microvolts — p=0.016

Primary: Baseline and Week 8scores on Children's Yale-Brown Obsessive Compulsive Scale - Pervasive Developmental Disorder Version — 12.7; 8.6 Scores on a scale

Primary: Change in ASD Symptoms Social Responsiveness Scale 2 (SRS-2) Scale From Baseline to Week 8 — -39.5; -29 scores on a scale

Primary: A Number of Participants With Non-serious and Serious Adverse Events 24 Hrs Post-transfusion — 0; 0; 0; 0 participants

Primary: Pediatric Anxiety Rating Scale — 7.79; 15.06 units on a scale

Primary: Children's Yale-Brown Obsessive Compulsive Scale Modified for Autism Spectrum Disorder (CY-BOCS-ASD) - Total Score — 14.81; 14.60; 14.94; 15.71 Score on a Scale

Primary: Change in Autism Symptoms — -6.77 units on a scale — p=<0.05