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Phase 4 Completed N=98 Randomized Single-blind Supportive Care

Applying Num Vapocoolant Spray to Cervix Before Paracervical Block to Decrease Pain During Gynecology Procedures

Pain With Paracervical Block · Pain With Gynecology Procedure · Postoperative Pain
Source: ClinicalTrials.gov NCT06227052 ↗
Enrolled (actual)
98
Serious AEs
0.0%
Results posted
Sep 2025
Primary outcomePrimary: Pain With Paracervical Block — 27; 20 units on a scale
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

The purpose of this study is to assess if Num vapocoolant spray decreases pain associated with paracervical block in gynecology procedures.

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain With Paracervical Block
27; 20
SECONDARY
Patient Satisfaction With Procedure
91.5; 94; 82; 75
SECONDARY
Provider Ease of Use
0; 0
SECONDARY
Other Pain Points During Gynecology Procedure
1; 0; 17; 9; 53; 56
SECONDARY
Pre Procedure Anxiety
59; 48

Eligibility Criteria

Inclusion Criteria

  • Age 18 years of age or older

Undergoing a procedure requiring paracervical block

English-speaking

Able and willing to sign the informed consent form and agree to terms of the study

Exclusion Criteria

  • Required or requested narcotics, anxiolytics, IV sedation, or general anesthesia for the procedure

Declines or has a contraindication/allergy to ibuprofen

Previously received vapocoolant spray in a medical setting

Contraindications or allergies to lidocaine for paracervical block or vapocoolant spray components (1,1,3,3-pentafluoropropaine or 1,1,1,2-tetrafluroethane)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06227052). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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