N/A
N=203
Potency and Precision Investigation
Depression, Anxiety
Bottom Line
View on ClinicalTrials.gov: NCT06240091 ↗Enrolled (actual)
203
Serious AEs
1.0%
Results posted
Feb 2025
Primary outcome: Primary: Working Alliance Inventory-Short Revised (WAI-SR), Total Scale — 3.63; 3.25; 3.95; 3.61 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- DISC-MA (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Woebot Health
- Primary completion
- May 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Working Alliance Inventory-Short Revised (WAI-SR), Total Scale |
3.63; 3.25; 3.95; 3.61; 3.72; 3.40 | — |
Summary
The overarching goal of this study is to establish initial proof of mechanism for precision interventions in an adult population.
Eligibility Criteria
Inclusion Criteria
- Must be 18-75 years of age
- Must own or have regular access to a smartphone with a recent operating system installed (Android: OS 8.0 or higher, Apple: iOS 13.0 or higher) with reliable Wi-Fi access or sufficient data plan to engage with assigned treatment condition for the duration of the study
- Must be available and committed to engage with the program and complete assessments for a 4-week duration
- Must be able to read and write in English
- Must have primary residence in the United States
- Must have mild or greater symptoms of depression and/or anxiety at Screening/Baseline, indicated by a score > 4 on the Patient Health Questionnaire (PHQ-8) and/or Generalized Anxiety Disorder (GAD-7)
Exclusion Criteria
- Current suicidal ideation with a plan and/or intent or a suicide attempt within the past 12 months
- Previous Woebot use
- Involuntary inpatient psychiatric hospitalization any time within the past 30 days
- Lifetime diagnosis of bipolar disorder
- Lifetime diagnosis of a psychotic disorder
Data sourced from ClinicalTrials.gov (NCT06240091). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.