N/A N=200 Depression and Anxiety in Rheumatoid Arthritis
Rheumatoid Arthritis · Depression · Anxiety
Primary: Hospital Anxiety and Depression Scale (HADS) — 107; 46; 20; 27 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=40 Depression, Epinephrine, and Platelet Function
Major Depressive Disorder
Primary: Response of Participants, Defined by Change in the 21-item Hamilton Depression Rating Scale (HDRS) From Baseline to Week8 — 5; 9; 2; 4 participants — p=.918
N/A N=1,206 Epidemiology of Depression, Anxiety, and Cognitive Impairment
Depression · Anxiety · Cognitive Impairment
Primary: Participants With Depression by Patient Health Questionnaire - 9 — 177 participants
N/A N=50 Efficacy and Feasibility of a Personalized Treatment for Depression With Co-Occurring Anxiety
Depression · Anxiety
Primary: Number of Participants Meeting Depression Remission Criteria — 10; 15 participants
N/A N=205 Depression Attention for Women Now (The DAWN Study)
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
Phase 4 N=69 Anxiety and Depression in Epilepsy: A Treatment Study
Anxiety · Depression · Epilepsy
Primary: Adherence to Intervention — 2; 0; 0 Participants
N/A N=30 EMR Outcomes: Anxiety and Depression in Epilepsy
Quality of Life · Anxiety · Depression
Primary: Percentage of Participants Retained in the Study in the EMR Arm — 67 percentage of participants
N/A N=57 Improving Depression Management
Depression
Primary: Patient Health Questionnaire (PHQ-9) — 12.6; 15.2 score on a scale
N/A N=116 Mindfulness, Group Therapy and Psychosis; Training Decreases Anxiety and Depression
Psychosis
Primary: Change in Generalized Anxiety Disorder-7 Pre/Post Test at Week 5 — 4.68; 6.28; 3.96; 7.38 units on a scale — p=0.003
N/A N=63 Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
Opioid-use Disorder · Anxiety Disorders · Depressive Disorder
Primary: Change in Anxiety Symptoms as Assessed by Generalized Anxiety Disorder- Q-IV Scale — -1.8; -1.04; -2.47; -1.53 units on a scale — p=.755
N/A N=60 A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19
Depression
Primary: Phase I - Feasibility (Eligibility) — 35; 25 Participants
N/A N=56 Anxiety in Older Veterans
Anxiety Disorders
Primary: Change in Anxiety Symptoms — 1.77; -2.42 units on a scale
N/A N=15 Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Rates of Depression
Depression
Primary: Skills of Cognitive Therapy (Patient Version) — 24.231; 24.231 units on a scale
N/A N=64 Virtual Reality Compared to Screen Based Engagement on Mood
Virtual Reality
Primary: Change in Positive Affect and Negative Affect From Baseline to After a 2 Minute Mood Induction — 3.7; 4.63; 1.97; 1.56 units on a scale
N/A N=15 The S.M.A.R.T. Project: Stress Management and Resilience Training for Teens
Depression Mild · Resilience, Psychological · Adolescent Behavior
Primary: Time to Incident Depression — 36; 18.86 weeks — p=0.02
N/A N=294 Comprehensive vs. Assisted Management of Mood and Pain Symptoms
Pain · Depression · Anxiety
Primary: Composite Z-score of Pain-anxiety-depression Severity — -0.52; -0.65 units on a scale
N/A N=392 Intervention Study of Depression in Breast Cancer Patients
Breast Cancer · Depression · Anxiety
Primary: Hamilton Depression Rating Scale (HAMD-17) — 11.52; 13.31; 11.01; 10.23 units on a scale
Phase 4 N=183 A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients
Depression · Generalized Anxiety Disorder · Panic Disorder
Primary: Change in Mental Health-related Quality of Life From Baseline to 24 Weeks — 8.87; 8.39 units on a scale — p=0.002
N/A N=29 Positive Valence System Enhancement Treatment for Anxiety and Depression: Clinical Efficacy and Neural Changes
Anxiety Disorders and Symptoms · Depression
Primary: Change From Baseline in Positive Affect (Positive and Negative Affect Schedule; Modified Differential Emotions Scale; Composite) — -0.41; -0.40; 0.73; -0.02 z-score
N/A N=100 Treatment of Depression in Acute Coronary Syndrome (ACS) Patients
Depression
Primary: Depression and Well-being Improvements After Cognitive-Behavioral Therapy and Well-Being Therapy as Assessed by Changes in Clinical Interview for Depression, Compared to…
N/A N=880 Tools for Anxiety and Depression Screening in Epilepsy
Epilepsy
Primary: Percentage of Subjects Completing Screening Instruments — 0; 14; 19; 12 Percentage who completed
Phase 4 N=106 Aging Brain Changes, Executive Dysfunction and Depression
Depression
Primary: Hamilton Depression Rating Scale. — 8.09 units on a scale
N/A N=84 Spirituality Teaching Program for Depressed Adults
Major Depression
Primary: Hamilton Depression Rating Scale - Depression Severity — 20.4; 20.3; 11.9; 18.0 units on a scale
N/A N=94 Stress and the Sympathetic Nervous System in Adults With Depression
Major Depressive Disorder
Primary: Percent of Days Participants Report Stressors — 36; 40 percent of days
Phase 2 N=902 An Expert System to Reduce Depression in Primary Care
Depression · Depressive Disorder, Major
Primary: Change in Depression Severity — -5.4; -3.7 units on a scale — p=.003
Phase 4 N=17 Ketamine Infusion for Adolescent Depression and Anxiety
Major Depressive Disorder · Anxiety Disorder
Primary: Montgomery-Asberg Depression Rating Scale Score 1 Day After Infusion — 15.44; 24.13 units on a scale
N/A N=33 Mindfulness Intervention to Study the Neurobiology of Depression
Depression
Primary: Change in Children's Depression Rating Scale - Revised — 27.47; 28.00; 25.53; 31.86 units on a scale
Phase 2 N=8 Healthy Heart Habits
Acute Coronary Syndrome · Depression
Primary: Acceptability Measured by the Client Satisfaction Questionnaire — 30.57 score on a scale
Early Phase 1 N=39 Defining and Treating Depression-related Asthma
Asthma · Depression · Childhood Asthma
Primary: FEV1 Percent Change Post-ipratropium — 10.8 percent change — p=0.032
N/A N=16 Testing TRUST Depression Management Intervention
Depressive Symptoms · Quality of Life
Primary: Patient Health Questionnaire-8 Adolescent — 6.17; 9.43; 6.80; 8.29 units on a scale