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N/A N=928 Randomized Prevention

Little Cigar and Cigarillo Warnings for Youth

Little Cigars and Cigarillos (LCC) Use

Enrolled (actual)
928
Serious AEs
Results posted
Dec 2025
Primary outcome: Primary: Willingness to Use Little Cigars Cigarillos (LCCs) — 2.86; 3.08; 2.99 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
FDA warnings + Image (Behavioral); FDA Warnings Text-Only (Behavioral); Surgeon General Text-Only Warnings (Behavioral)
Age
Pediatric, Adult · 15+ yrs
Sex
All
Sponsor
UNC Lineberger Comprehensive Cancer Center
Primary completion
Nov 2024

Outcome Measures

OutcomeResultp-value
PRIMARY
Willingness to Use Little Cigars Cigarillos (LCCs)
2.86; 3.08; 2.99
SECONDARY
Past 7 Days Little Cigar Use
1.92; 1.86; 1.88
SECONDARY
Past 7 Days Cigarillo Use
1.93; 1.86; 1.82
SECONDARY
Little Cigar and Cigarillos (LCCs) Susceptibility
2.33; 2.49; 2.46
SECONDARY
Cognitive Elaboration About Risk of Little Cigar and Cigarillo Use
4.12; 3.99; 4.00
SECONDARY
Warning Negative Affect/Worry
3.90; 3.79; 3.79
SECONDARY
Knowledge of Little Cigar and Cigarillo (LCC) Harms
10.06; 10.12; 9.71
SECONDARY
Beliefs About Little Cigar and Cigarillo (LCC) Harms
4.30; 4.31; 4.24
SECONDARY
Cognitive Elaboration About Risk of Little Cigar and Cigarillo Use
4.12; 3.99; 4.00
SECONDARY
Cognitive Elaboration About Risk of Little Cigar and Cigarillo Use
4.12; 3.99; 4.00
SECONDARY
Cognitive Elaboration About Risk of Little Cigar and Cigarillo Use
4.12; 3.99; 4.00
SECONDARY
Cognitive Elaboration About Risk of Little Cigar and Cigarillo Use
4.12; 3.99; 4.00
SECONDARY
Cognitive Elaboration About Risk of Little Cigar and Cigarillo Use
4.12; 3.99; 4.00
SECONDARY
Cognitive Elaboration About Risk of Little Cigar and Cigarillo Use
4.12; 3.99; 4.00
SECONDARY
Warning Negative Affect/Worry
3.90; 3.79; 3.79
SECONDARY
Warning Negative Affect/Worry
3.90; 3.79; 3.79
SECONDARY
Warning Negative Affect/Worry
3.90; 3.79; 3.79
SECONDARY
Warning Negative Affect/Worry
3.90; 3.79; 3.79
SECONDARY
Warning Negative Affect/Worry
3.90; 3.79; 3.79

Summary

This study explores the effect of the little cigars and cigarillos (LCC) warnings on youth who currently use, have ever used, or are susceptible to using LCCs. This study will inform the Food and Drug Administration (FDA) implementation of LCC warnings, which can reduce LCC use and lessen tobacco health disparities among youth.

Eligibility Criteria

Inclusion Criteria

  • Members of the recruitment panel (we are partnering with a panel provider for the recruitment of all participants)
  • Agree to provide their honest answers
  • Susceptible to using LCCs, or have ever used little cigars and/or cigarillos, or currently use little cigar and/or cigarillos in the past 30 days
  • Age 15 - 20 years old
  • Currently living in US or US territory
  • Able to complete 2 surveys that take approximately 15 minutes
  • Able to complete a 2-minute survey each day for 6 days
  • Able to verify they are not a bot using CAPTCHA
  • Able to answer a simple, random math question

Exclusion Criteria

  • Not able to verify they are not a bot using Completely Automated Public Turing test to tell Computers and Humans Apart (CAPTCHA).
  • Not able to answer a simple, random math question.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06413797). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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