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Phase 3 Completed N=19 Randomized Treatment

Implications of Fecal Microbiota Transplantation in Modulating the Effects of Liver Cirrhosis

Source: ClinicalTrials.gov NCT06478602 ↗
Enrolled (actual)
19
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcomePrimary: Liver Stiffness by Transient Elastography (FibroScan) — 22.6; 23 kPa
◆ Published Evidence
Established ▲ Trending
21citations · ~21 / year
Fecal Microbiota Transplantation in Patients with Alcohol-Associated Cirrhosis: A Clinical Trial.
Journal of clinical medicine · 2025 · Open access · High-confidence link

Summary

The study aims to investigate the beneficial effects of fecal transplantation in patients diagnosed with liver cirrhosis (regardless of etiology).

Linked Publications (2)

  • Fecal Microbiota Transplantation in Patients with Alcohol-Associated Cirrhosis: A Clinical Trial.
    Journal of clinical medicine · 2025 · 21 citations · Open access · High-confidence link
  • Dynamics of Fecal microRNAs Following Fecal Microbiota Transplantation in Alcohol-Related Cirrhosis.
    Journal of clinical medicine · 2025 · 0 citations · Open access · High-confidence link

Outcome Measures

OutcomeResultp-value
PRIMARY
Liver Stiffness by Transient Elastography (FibroScan)
22.6; 23
PRIMARY
Implications of Fecal Microbiota Transplantation in Modulating Hepatic Encephalopathy
5; 3; 1; 7; 0; 3

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of liver cirrhosis according to current protocols.
  • Conscious and cooperative adult patients.

Exclusion Criteria

  • Patients with hemodynamic and/or respiratory instability.
  • Patients with contraindications for colonoscopy or fecal transplantation.
  • Patients with acute or chronic infections with HIV, Tuberculosis, MDR Enterobacteria, CMV, parasites, fungi.
  • Associated oncological pathology.
  • Patients with other causes of severe immunodeficiencies.
  • Lack of compliance with the conditions imposed by the research project.
  • Patients who do not sign the informed consent.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06478602) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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