Patient Buddy App reduced avoidable readmissions in cirrhosis inpatients compared to standard of care.
App helps cirrhosis patients avoid hospital readmission
This randomized clinical trial enrolled 464 subjects (232 dyads) with cirrhosis in a multicenter setting. The Patient Buddy App (HIT) signif…
A smartphone app cut avoidable hospital readmissions in half for cirrhosis patients, a new trial shows.
Systematic review links periodontitis to NAFLD progression and HCC risk
Your Mouth Could Be Harming Your Liver—Here’s What to Do
This systematic review finds that periodontitis and oral pathogens like F. nucleatum are independent risk factors for NAFLD progression, cir…
You brush your teeth every day. You might floss sometimes.
Integrative review of Epimedium flavonoids in hepatitis and cirrhosis shows preclinical promise but lacks clinical validation.
Ancient Herb Shows New Promise for Liver Scarring and Hepatitis
This integrative review synthesizes data from 33 high-impact studies regarding Epimedium species and its bioactive flavonoids, icariin and i…
This research suggests a traditional herb may offer a new way to protect the liver, but more work is needed to prove it’s safe and effective…
Observational study links semaglutide dose and weight loss to lower liver disease risk.
Study links semaglutide use to lower risk of several liver conditions in patients with liver disease
This observational study from a real-world federated EHR network analyzed 6,734 patients with liver disease. It found associations between h…
Higher semaglutide doses and greater weight loss were linked to lower risks of steatohepatitis, alcoholic liver disease, and death in patien…
Review of liver disease immunomodulation strategies notes precision over broad suppression
Your Liver's Immune Cells Play Both Hero and Villain at Once
This narrative review examines immunomodulation approaches for liver diseases, including acute liver injury, HBV infection, MASLD/MASH, fibr…
Liver immune cells can both damage and repair your organ at the same time, a discovery that could unlock new precision treatments for hepati…
Meta-analysis links rare APOB variants to advanced MASLD, cirrhosis, and hepatocellular carcinoma across large cohorts
Do rare gene changes linked to liver disease also raise your risk for cancer and scarring?
This meta-analysis reviews data from the Million Veteran Program, UK Biobank, and clinical cohorts to assess rare APOB variant carriage in p…
Rare gene changes linked to fatty liver disease also raise your risk for liver cancer and severe scarring, according to new findings.
Review of bile acid homeostasis regulation in liver disease and cancer
Review of bile acid regulation for liver disease conditions shows limited evidence
This narrative review examines the regulation of bile acids homeostasis in conditions including cholestasis, hepatic fibrosis, cirrhosis, he…
Bile acid imbalance drives liver disease, but this review found no data proving that regulating it safely treats conditions like cirrhosis o…
Oral nutritional interventions associated with reduced clinical events in adults with cirrhosis
Can better nutrition help people with advanced liver disease?
A systematic review and meta-analysis of 3,128 adults with cirrhosis found oral nutritional interventions were associated with reduced risks…
Better nutrition linked to fewer hospital visits and lower risk of serious problems for adults with advanced liver disease.
Corticosteroids in cirrhotic shock show no mortality benefit but increase bleeding and organ failure risk
Corticosteroids help resolve shock in cirrhosis patients but don't improve survival
A meta-analysis of 514 cirrhotic patients with septic or distributive shock found low-dose corticosteroids did not reduce in-hospital mortal…
Low-dose corticosteroids help resolve shock in cirrhosis patients but do not improve overall survival and increase bleeding risks.
Pilot trial finds no between-group muscle mass benefit from HMB supplement in cirrhosis sarcopenia
Small pilot study tests nutritional supplement for muscle loss in liver cirrhosis
A pilot randomized controlled trial of 21 patients with stable decompensated cirrhosis and sarcopenia found no significant between-group dif…
A nutritional supplement with HMB improved leg strength and body composition in cirrhosis patients, though it did not increase overall muscl…
Continuous terlipressin infusion reduces treatment failure and rebleeding in acute variceal bleeding
Could a different way of giving a bleeding drug save more lives?
A meta-analysis of 6 RCTs (n=494) in cirrhosis patients found continuous terlipressin infusion reduced treatment failure (RR 0.32) and reble…
A slow drip of the bleeding drug terlipressin works better than a quick shot, causing fewer side effects and less rebleeding for patients wi…
SBRT as bridging therapy in advanced cirrhosis HCC patients shows 67% transplant eligibility at 1 year
Small study explores radiation therapy for liver cancer patients awaiting transplant
A prospective pilot trial in 9 HCC patients with Child-Pugh B8 or worse cirrhosis found that SBRT (40 Gy/5 fractions) as a bridging strategy…
A small study found that focused radiation therapy helped 67% of liver cancer patients with advanced scarring stay eligible for a transplant…