N/A Completed N=20 Prevention

Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome

Down Syndrome · Physical Inactivity

Source: ClinicalTrials.gov NCT06537648 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2026

Primary outcomePrimary: Attendance — 21.7 Number of Classes Attended

Summary

The investigators are assessing acceptability, appropriateness, and feasibility of an remote choreographed exercise intervention using validated scales alongside qualitative data among young adults with Down Syndrome. Participants will take part in a 12-week exercise program with two 35-minute session per week delivered in a group setting. The aims of the project are to: * Assess the feasibility of a 12 week remotely delivered group dance intervention. * Assess changes in aerobic fitness and cognitive function in response to a 12 week remotely delivered group dance intervention. * Assess the intensity and total energy expenditure of remotely delivered group dance sessions.

Outcome Measures

Outcome	Result	p-value
PRIMARY Attendance	21.7	—
PRIMARY Retention	20	—
PRIMARY Adverse Events	3; 1	—
SECONDARY Energy Expenditure	4.8	—
SECONDARY Exercise Intensity	90.1	—

Eligibility Criteria

Inclusion Criteria

Diagnosis of Down syndrome
Sufficient functional ability to communicate through spoken language
No plans to relocate outside the study area over the next 12 weeks
Possession of a personal device that allows for connectivity to the internet and participate in 2x weekly group video calls
Ability to participate in Moderate to vigorous physical activity

Exclusion Criteria

Serious medical risk (e.g., cancer, recent heart attack, stroke, pregnancy, angioplasty as determined by the research staff
unwilling to participate in outcomes assessments
uninterested

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06537648). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.