N/A N=20 Treatment

Cognitive Priming for Stroke Tele-rehabilitation

Stroke

Bottom Line

View on ClinicalTrials.gov: NCT06555302 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2026

Primary outcome: Primary: Change From Baseline in Global Cognition, as Measured by the Montreal Cognitive Assessment (MoCA) — 1.74 total score — p=.012

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Cognitive Rehabilitation (Behavioral); Occupational Therapy (Behavioral)
Age: Adult, Older Adult · 21+ yrs
Sex: All
Sponsor: Medical University of South Carolina
Primary completion: Apr 2025

Outcome Measures

Outcome	Result	p-value
PRIMARY Change From Baseline in Global Cognition, as Measured by the Montreal Cognitive Assessment (MoCA)	1.74	.012 sig
PRIMARY Change From Baseline Functional Task Performance and Activity Participation, as Measured by the Patient Specific Functional Scale (PSFS)	2.84	.000 sig
PRIMARY Change From Baseline Psychosocial Function (Depression), as Measured by the Patient Health Questionnaire (PHQ-9)	-0.26	.840
SECONDARY Change From Baseline Subjective Cognition, as Measured by the NeuroQoL-Cognitive Function	0.78	.697
SECONDARY Change From Baseline Functional Task Performance and Activity Participation, as Measured by the Performance Quality Rating Scale (PQRS)	0.53	.004 sig
SECONDARY Change From Baseline Functional Task Performance and Activity Participation, as Measured by the Stroke Self Efficacy Questionnaire (SSEQ)	6.79	.121
SECONDARY Change From Baseline Psychosocial Function (Global), as Measured by the Inventory of Psychosocial Functioning (IPF)	-1.32	.604
SECONDARY Change From Baseline Psychosocial Function (Sleep), as Measured by the PROMIS Sleep Disturbance	-2.58	.361

Summary

The goal of this pilot study is to investigate whether adding cognitive rehabilitation to an existing occupational therapy (OT) stroke telerehabilitation program will improve stroke survivors' functioning. The main question it aims to answer is whether this intervention improves cognition, participation, upper extremity use in real-world activities, and mood/quality of life. Participants will be asked to engage in an 8-week stroke tele-rehabilitation program (13 sessions), which includes both cognitive rehabilitation and OT for arm/hand function, and complete assessments before and after the intervention.

Eligibility Criteria

Inclusion Criteria

Have experienced ischemic or hemorrhagic stroke with resultant paresis of one arm/hand at least 30 days prior
Adults ages 21 years or older
Are able to speak and read English
Have corrected vision to be able to read text on a screen
Have a device on which a telerehabilitation visit can be conducted (i.e., phone, tablet, or laptop) and a Wi-Fi connection or cellular service
Able to participate in the study's assessment sessions as per the judgment of the licensed, experienced stroke telerehabilitation occupational therapist.

Exclusion Criteria

Have moderate-severe or severe aphasia.
Have impaired decision making capacity as determined by a standard protocol for assessing capacity to provide informed consent.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06555302). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.