N/A N=42

Added Sugar Intake and Brain Structure and Function

Child Development

Bottom Line

View on ClinicalTrials.gov: NCT06640829 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2025

Primary outcome: Primary: Added Sugars Intake Relationship to Brain Structure — 0.119; -0.231; 0.345; 0.384 Pearson correlation coefficient

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: —
Age: Pediatric · 5+ yrs
Sex: All
Sponsor: University of Kansas Medical Center
Primary completion: Jul 2024

Outcome Measures

Outcome	Result	p-value
PRIMARY Added Sugars Intake Relationship to Brain Structure	0.119; -0.231; 0.345; 0.384; 0.176; -0.202	—
PRIMARY Added Sugars Intake Relationship to Brain Function	0.059; -0.016; -0.045; 0.090; 0.481; 0.404	—
PRIMARY Fructose Intake Relationship to Brain Structure	-0.220; -0.413; -0.730; -0.071; 0.132; -0.535	—
PRIMARY Fructose Intake Relationship to Brain Function	-0.014; 0.018; -0.129; -0.275; -0.555; -0.331	—
SECONDARY Added Sugars Intake Relationship to Cognition Specifically Attention Development	0.163; -0.076; -0.031; -0.374; -0.259; 0.151	—
SECONDARY Added Sugars Intake Relationship to Cognition Specifically Vocabulary Receptiveness	0.118; 0.124; 0.062; 0.020; 0.035; 0.043	—

Summary

The purpose of this study is to learn if there is a relationship between added sugar intake during pregnancy, infancy, and toddlerhood and the brain's structure and function at 5-6 years old.

Eligibility Criteria

Inclusion Criteria

Participated in the ADORE GAINS study (R01 DK118220).
Age at participation 5-6 years old.

Exclusion Criteria

Did not participated in the ADORE GAINS study.
Younger than 5 and older than 6.
Autism diagnosis

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT06640829). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.