Phase 4
N=93
The Ultrasound Guided Pericapsular Nerve Group and Anterior Quadratus Lumborum Blocks in Hip Replacement Surgeries
Post Operative Analgesia
Bottom Line
View on ClinicalTrials.gov: NCT06679764 ↗Enrolled (actual)
93
Serious AEs
0.0%
Results posted
Jan 2026
Primary outcome: Primary: The Total Amount of Morphine Consumption — 6.0; 8.0; 12.0 mg of IV morphine — p=0.035
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Anterior quadratus lumborum block technique (AQLB) (Procedure); Pericapsular Nerve Group (PENG) block (Procedure); Control Group (Drug)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Cairo University
- Primary completion
- Sep 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Total Amount of Morphine Consumption |
6.0; 8.0; 12.0 | 0.035 sig |
| SECONDARY Numeric Pain Rating Scale at Rest Over First 24 Hours |
0.0; 1.0; 2.0; 1.0; 1.0; 2.0 | — |
| SECONDARY Numeric Pain Rating Scale During Passive 90° Hip Flexion Over First 24 Hours |
1.0; 1.0; 3.0; 2.0; 1.0; 5.0 | — |
| SECONDARY Time to First Rescue Morphine Analgesia |
12.0; 8.0; 2.0 | — |
| SECONDARY Manual Muscle Test (MMT) Score for Quadriceps/Iliopsoas Over First 24 Hours |
1.0; 2.0; 0.0; 1.0; 3.0; 1.0 | — |
| SECONDARY Active Hip Flexion Range of Motion (0°-90°) Over First 24 Hours |
0.0; 20.0; 0.0; 0.0; 30.0; 20.0 | — |
| SECONDARY Total Intraoperative Fentanyl Dose |
142.58; 152.90; 236.61 | — |
| SECONDARY Time to First Walk |
24.0; 8.0; 18.0 | — |
| SECONDARY Length of Hospital Stay |
3.16; 2.13; 2.94 | — |
Summary
The investigators hypothesis that PENG block will produce effective opioid sparing analgesia with enhanced motor recovery more than AQLB in elderly patients undergoing total hip replacement surgeries
Eligibility Criteria
Inclusion Criteria
- Both genders
- Type of surgery; unilateral elective total hip replacement.
- Physical status ASA I- III
- Age ≥ 65 Years.
- Body mass index (BMI): > 20 kg/m2 and 3 folds) or severe kidney disease (creatinine >2).
- long operative time more than 3 hours.
Data sourced from ClinicalTrials.gov (NCT06679764). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.