N/A
N=30
Efficacy of Photobiomodulation Therapy Using 980nm Versus 635nm Diode Lasers for Treatment of Myofascial Pain
Myofascial Pain Syndrome
Bottom Line
View on ClinicalTrials.gov: NCT07069764 ↗Enrolled (actual)
30
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcome: Primary: Pain Intensity Reduction — 7.6; 7.8; 3.2; 2.5 "units on scale — p=0.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Doctor smile 635nm For Arm 1 (Device); Doctor smile 980 nm For Arm2 (Device)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- National Institute of Laser Enhanced Sciences
- Primary completion
- Mar 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Intensity Reduction |
7.6; 7.8; 3.2; 2.5; 2.9; 2.1 | 0.05 |
| SECONDARY Maximum Mouth Opening (MMO) |
34.5; 34; 41.3; 43.5; 42.1; 44.2 | — |
| SECONDARY Lateral Jaw Movements |
6.2; 6.0; 8.3; 8.7; 8.5; 8.8 | — |
| SECONDARY Changes in Muscle Activity Measured by Surface Electromyography (sEMG) |
15.8; 15.5; 8.9; 9.9; 16.1; 15.9 | — |
| SECONDARY Protrusive Movements |
5.8; 5.9; 7.4; 7.8; 7.5; 8.0 | — |
Summary
This randomized controlled clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) using two different diode laser wavelengths (980 nm and 635 nm) in the treatment of myofascial pain associated with temporomandibular disorders (TMD). The study compares pain reduction and muscle activity improvement using surface electromyography (sEMG) before and after laser application. Participants are randomly assigned to receive either 980 nm or 635 nm laser treatment twice per week for five weeks. The primary outcomes include pain intensity and functional mandibular movements, while secondary outcomes assess changes in sEMG recordings.
Eligibility Criteria
Inclusion Criteria
- - patients with myofascial pain due to stress, medically free, not to resort to self-medication during the study period with no chronic diseases.
Exclusion Criteria
- Patients with TMJ disorders either due to bony degeneration changes or soft tissue changes.
- Patients with pain of dental etiology were excluded, pregnancy, lactation, cardiac arrhythmia, diabetic patients, erosions and medically free.
- Patient with history of malignancy or a history of previous surgery of neck and/ shoulder within the past year of the study were excluded.
- Any patients had treatment that can affect muscles will be excluded, either pharmacological treatment (e.g, opioids, morphine, muscles relaxants or anti-depressants), physiotherapy management and occlusal splints.
Data sourced from ClinicalTrials.gov (NCT07069764). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.