Phase 4 N=55 Triple Combination Therapy in High Risk Crohn's Disease (CD)
Crohn Disease
Primary: Percentage of Participants Achieving Endoscopic Remission at Week 26 — 34.5 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=32 Minocycline and Tobacco Craving in Smokers With Schizophrenia
Schizophrenia · Tobacco Use
Primary: Questionnaire for Smoking Urges-Brief — 42.1429; 38.6429; 43.4286; 36.8571 score on a scale
Phase 4 N=62 Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors
Pituitary Tumor · Pain
Primary: Comparison of Mean Pain Scores Between Two Arms (Measured Every 4 Hours Over 48 Hour) — 1.7; 2.8 0-10 units on a scale
Phase 4 N=96 12 Versus 20 mL PCB for D&E Cervical Prep
Pain
Primary: Pain Immediately Following Dilator Insertion — 41; 49 score on a scale
Phase 4 N=70 Can Vitamin D Reduce Heart Muscle Damage After Bypass Surgery?
Vitamin D Deficiency · Cardiomyopathies · Apoptosis
Primary: Caspase 2 Enzyme Level — 1.3; 2.0 cells/ HPF
Phase 4 N=42 Dynamics of Inflammation and Its Blockade on Motivational Circuitry in Depression
Depression
Primary: Effort-based Decision-making (EBDM) Task Score — 2.13; 2.09; 1.85; 2.78 score on a scale
Phase 4 N=44 Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration
Retinal Degenerations
Primary: Number of Participant With Improvement in Foveal Thickness (Macular Fluid) as Measured by Optical Coherence Tomography (OCT) — 36 participants
Phase 4 N=211 A Study to Evaluate the Safety of Nivolumab and Ipilimumab in Subjects With Previously Untreated Advanced or Metastatic Renal Cell Cancer
Renal Cell Carcinoma
Primary: Number of Participants With High Grade (Grade 3-4) Immune Mediated Adverse Events (IMAEs) — 1; 0; 0; 0 Participants
Phase 4 N=465 Immunologic Response to FluMist vs. Flucelvax
Influenza, Human · Immune Response
Primary: Number of Participants With Seroconversion Response In 2019 — 5; 33; 11; 44 Participants — p=<0.001
Phase 4 N=164 Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair
Analgesia, Postoperative
Primary: Cumulative Opioid Requirements for 72 Hours After Surgery — 325; 350; 310 mg morphine equivalents/day
Phase 4 N=10 Remission Through Early Monitored Insulin Therapy - Duration Month
Type 2 Diabetes Mellitus
Primary: Change in Baseline A1C and A1C Measured at 3 Month Intervals up to 12 Months — 9.00; 6.81; 7.13; 7.26 percentage of glycosylated hemoglobin
Phase 4 N=10 Sphenopalatine Ganglion Blocks RCT
Migraine
Primary: Number of Participants With a Reduction in Headache Days From Baseline to Month 8 of Treatment — 3; 1; 1; 0 participants
Phase 4 N=14 Effects of PCSK9 Inhibition by Evolocumab on Postprandial Lipid Metabolism in Type 2 Diabetes
Type 2 Diabetes Mellitus
Primary: Mean ApoB Concentration Before and After Evolocumab — 75.9; 35.3 mg/dL — p=<0.001
Phase 4 N=221 Study to Collect Information on How Well the Study Drug Naproxen Sodium Tablets Works Compared to Hydrocodone/Acetaminophen Tablets in Order to Relieve Pain in Participants Experiencing Moderate to Severe Pain After Having Their Wisdom Teeth Removed
Pain
Primary: Sum of Pain Intensity Difference Over 12 Hours (SPID 0-12) — 53.20; 38.39; 13.57 Scores on a scale*hours — p=0.001
Phase 4 N=66 Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery
Pain, Postoperative · Pelvic Organ Prolapse
Primary: Visual Analog Scores (VAS) — 20; 40 mm