Phase 2 N=24 Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes
Type 2 Diabetes
Primary: Change in Absolute Gluconeogenesis From Baseline to 12 Weeks — 0.018; -0.050 mg/kg LBM/min
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=843 Personalized Health Assessment Related to Medications (Project PHARM)
Feedback, Psychological · Clinical Trial · Substance Abuse
Primary: Change in Past 6 Month Non-Medical Use of Prescription Stimulant Medication Frequency — -2.04; -1.72; -1.03; -.38 Usage days — p=0.03
Phase 2 N=67 "SMART-FM": Smart-Phone Based Digital Therapeutic for Management of Fibromyalgia
Fibromyalgia
Primary: Revised Fibromyalgia Impact Questionnaire (FIQ-R) Total Score — -8.7; -3.0 score on a scale
Phase 2 N=35 A Study of Flurpiridaz (18F) Injection for PET Imaging for Assessment of MPI Quality Using HPLC and SPE Manufacturing Processes
Coronary Artery Disease (CAD) · Ischemic Heart Disease
Primary: Intra-reader Difference of Summed Rest Score (SRS) for Positron Emission Tomography (PET) Myocardial Perfusion Imaging (MPI) — 6.662; 6.513; 6.235; 6.219 score on a…
Phase 2 N=51 Avoiding Treatment in the Hospital With Furoscix for the Management of Congestion in Heart Failure - A Pilot Study
Heart Failure
Primary: Win Ratio of Composite Endpoint — 228; 206 Number of Wins for the group
Phase 2 N=166 A Study of Accelerated 3 Fraction Photon,Proton or Brachytherapy for Early Invasive and Noninvasive Breast Ca
Breast Cancer
Primary: Change in the Rate of Adverse Cosmesis (Defined as Fair or Poor Cosmesis) Compared to Baseline Using the Harvard Cosmetic Rating: — 2; 0; 0 Participants
Phase 1 N=92 Healthy Minds Program App Dosage
Depression · Anxiety · Psychological Distress
Primary: Randomization Rate: Number of Participants Who Were Randomized and Completed EMA Assessments and Activities in the HMP App — 46; 46 Participants
N/A N=13 Efficacy and Safety of ICD Remote Monitored Exercise Testing to Improve Heart Failure Outcomes: REMOTE HF-ACTION
Heart Failure
Primary: Abbott Implantable Cardioverter-defibrillator (ICD) or Cardiac Resynchronization Therapy Defibrillator (CRT-D) Device Measured Daily Physical Activity (PA) — 129.3…
Phase 2 N=8 Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant
Acute Biphenotypic Leukemia · Acute Lymphoblastic Leukemia · Acute Myeloid Leukemia
Primary: Number of Participants With Relapsed Leukemia — 3; 5 Participants
Phase 2 N=249 A Study of CIN-107 in Patients With Uncontrolled Hypertension
Uncontrolled Hypertension
Primary: Change From Baseline in Mean Seated Systolic BP (SBP) — -16.6; -17.0; -16.0; -19.8 mmHg
N/A N=63 Minoxidil 5% / Botanical Hair Regimen in Men With Thinning Hair and Male Pattern Hair Loss/Androgenic Alopecia
Male Pattern of Hair Loss, Androgenic Alopecia
Primary: Change From Baseline in Investigator's Rating of Standardized Global Photographs at Week 12 — 5.0; 5.1; 5.1; 5.1 Score on a scale
Phase 1 N=18 A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults
Healthy
Primary: Area Under the Plasma Concentration Versus Time Curve, From Time 0 to the Last Measurable Concentration (AUC0-t) of Total Molybdenum (Mo) — 14531; 18537; 14536 hours*ng/mL
N/A N=43 enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars
Acne Scars - Mixed Atrophic and Hypertrophic
Primary: Correct Identification of the 12 Weeks Post-final Treatment Photographs From the Baseline Photographs by at Least 2 of the 3 Blinded Reviewers in 75% of the Patients…
Phase 4 N=57 Addition of Buprenorphine to Paracervical Block for Pain Control During Osmotic Dilator Insertion
Procedural Pain · Buprenorphine · Adjuvants, Anesthesia
Primary: Pain Score at the Time of Osmotic Dilator Insertion — 3.5; 4.0 score on a scale
Phase 2 N=55 COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications
Covid19 · Coronavirus Infection
Primary: World Health Organization (WHO) Ordinal Scale Score — 26; 22; 1; 2 Participants