Phase 4 N=20 The Impact of Contact Lens Coefficient of Friction (CoF) on the Development of Lid Wiper Epitheliopathy (LWE)
Lid Wiper Epitheliopathy
Primary: Lid Wiper Epitheliopathy — 0.63; 0.25 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=19 Study to Evaluate the Feasibility of [18F]Florbetapir PET for Assessment in MS Patients
Multiple Sclerosis
Primary: Total Number of Lesions Detected by [18F]Florbetapir PET — 194 Lesions
Phase 4 N=40 Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)
Sickle Cell Disease · Renal Function Disorder
Primary: Measure of Plasmatic Data: Maximum Concentration (Cmax) — 271.8; 316.8; 260.2 Micromolar
Phase 4 N=21 The Effect of Donepezil on Gait and Balance in Parkinson's Disease
Parkinson's Disease
Primary: Sensory Organization Test - Composite Score — 7.7; 0.6 score on a scale
Phase 4 N=102 Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation
End-stage Renal Failure · Graft Rejection
Primary: Patient Survival With a Functioning Graft — 92.3; 96 percent of participants — p=0.26
Phase 4 N=124 Clinical Trial of Efficacy and Safety of Divaza for Adjustment of Oxidative Disorders in Patients With Cerebral Atherosclerosis
Cerebral Atherosclerosis
Primary: Change in Mean Value of Lipoprotein Resistance to LPO. — 42.4; 42.9; 55.6; 49.4 seconds — p=0.007
Phase 4 N=59 A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment
Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
Primary: Change From Baseline in Rasch-transformed Score of FACE-Q Satisfaction With Facial Appearance Overall Scale to End of Study — 40.9; 37.8; 21.5; 32.9 score on a scale…
Phase 4 N=36 Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures
Drug Effect · Rib Fractures · Rib Trauma
Primary: Daily Sequential Clinical Assessment of Respiratory Function (SCARF) Score — 2; 2 score on a scale — p=0.12
Phase 4 N=113 An Open-Label, Single Arm Study of Obinutuzumab Short Duration Infusion in Patients With Previously Untreated Advanced Follicular Lymphoma
Advanced Follicular Lymphoma
Primary: Percentage of Grade >=3 Infusion-Related Reactions (IRRs) During Cycle 2 in Patients Who Had Previously Received Obinutuzumab at the Standard Infusion Rate During Cycle…
Phase 4 N=19 Treatment of Adolescent Antimuscarinic (Anticholinergic) Toxidrome
Anticholinergics Toxicity
Primary: Comparison of RASS Score Between Physostigmine and Lorazepam: Before Bolus — 1.5; 1 score on a scale
Phase 4 N=10 Effect of Increasing Doses of Cystine Binding Thiol Drugs on Cystine Capacity in Patients With Cystinuria
Cystinuria
Primary: Cystine Capacity — 43.1 mg/L
Phase 4 N=60 Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters
Hypogonadism, Male
Primary: Change in Testosterone Levels From Baseline to 27 Weeks — 652 ng/dL
Phase 4 N=47 Nailfold Capillary Blood Flow With Latanoprost Bunod
Glaucoma, Open-Angle
Primary: NFC Blood Flow at Baseline and 15 Minutes — 72.52; 83.94; 93.01; 60.50 pL/s
Phase 4 N=40 Improving Post-Operative Pain and Recovery in Gynecologic Surgery
Postoperative Pain · Opioid Use · Acetaminophen
Primary: Postoperative Pain: Standardized Pain Scale — 2.82; 3.18 score on a scale — p=.378
Phase 4 N=25 Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Hearing Loss · Depression
Primary: Hamilton Rating Score for Depression (HRSD) — 12.04; 13.86 score on a scale