Phase 2 N=34 Sex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric Acid
Diabetes Mellitus, Type 2 · Hyperuricemia
Primary: Carotid Femoral Pulse Wave Velocity (cfPWV) — 8.71; 7.8; 8.28 m/s
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=349 Extravascular ICD Pivotal Study
Tachycardia · Ventricular Arrythmia
Primary: Safety Outcome - Freedom From Major Complications Related to the EV ICD System and/or Procedure at 6 Months Post-implant — 293 Participants — p=<0.0001
Phase 2 N=31 Low Dose Radiation Therapy for Glioblastoma Multiforme
High Grade Glioma
Primary: Response Rate
Phase 2 N=26 Network-Level Mechanisms for Preclinical Alzheimer's Disease Development
APOE 4
Primary: Functional Connectivity Strengths of Neural Networks — 0.233; 0.318 Pearson coefficient — p=0.007567
N/A N=27 REALIsM-HF Pilot Study
Heart Failure
Primary: Daily Steps Count — 5052; 3509; 6627; 2524 Steps
N/A N=36 Mindfulness-Based Resilience Training for Aggression, Health, and Stress Among Law Enforcement Officers
Stress, Psychological · Aggression
Primary: Change in Aggression — 1.94; 1.67; 1.85; 1.72 score on a scale
N/A N=208 Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial
HIV Infections
Primary: Visual Analog Scale (VAS) of Self-Reported Antiretroviral Adherence — 85.71; 85.53 Unit on a scale
N/A N=116 Promotion of Physical Activity in Adolescents With Intellectual and Developmental Disabilities
Adolescent Behavior · Intellectual Disability · Down Syndrome
Primary: Change in Adolescent Physical Activity From Baseline to 6 Months — -3.2; -0.6 minutes per day
Phase 2 N=80 Optilume™ BPH Prostatic Drug Coated Balloon Dilation Catheter
Benign Prostatic Hyperplasia · Benign Prostatic Hypertrophy
Primary: Therapeutic Responder at 3 Months — 65 Participants
Phase 3 N=482 A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine
Migraine · Migraine With Aura · Migraine Without Aura
Primary: Percentage of Participants With Attacks With Sustained Freedom From Headache Pain 2-48 Hours (Modified Intent to Treat Population) — 40.0 Participants
N/A N=60 Health Effects of Secondhand Smoke Exposure in Outdoor Smoking Areas in Patients With COPD and Asthma ( TackSHSWP5 )
COPD · Asthma · Second Hand Tobacco Smoke
Primary: Respiratory Rate — 21.66; 21.57 BR/M breathing rate per min
Phase 2 N=23 VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2
Anal Neoplasm
Primary: Percentage of Participants With no Histologic Evidence of Anal or Anal/Peri-Anal HSIL and no Evidence of HPV-16/18 at Week 36 — 9.1 percentage of participants — p=0.8633
Phase 2 N=12 Efficacy of Doxycycline on Metakaryote Cell Death in Patients With Resectable Pancreatic Cancer
Resectable Pancreatic Cancer
Primary: Determine the Efficacy of Doxycycline in Inducing Metakaryotic Cell Death in Primary Pancreatic Tumors as Measured by Pathologic Response — 8.9 Cells/g
Phase 4 N=9 Impact of Beta-blockers on Physical Function in HFpEF
Heart Failure · Heart Failure, Diastolic · Heart Failure With Preserved Ejection Fraction
Primary: Change in Physical Activity When on Beta-blocker Versus When Off Beta-blocker, as Measured by Step Count on Wearable Activity Monitoring Device — 2790.5; 3167.3 Count of…
Phase 2 N=60 Testing the Ability of JNJ-18038683 to Improve Cognition and Reduce Depressive Symptoms in Stable Bipolar Patients
Bipolar Disorder
Primary: The 8-week Evaluation of Verbal Fluency Performance After Randomization — 39.44; 41.12 score on a scale — p=<0.05