65,437 trials
Fecal Incontinence · Bile Acid Malabsorption
Primary: Number of Participants to Report a 50% or Greater Reduction in Weekly Fecal Incontinence (FI) Episodes — 17; 13 Participants — p=0.85
Depression, Postpartum
Primary: Change From Baseline (CFB) in the 17-item Hamilton Rating Scale for Depression (HAM-D) Total Score at Day 15 — 28.8; 28.6; -11.4; -15.6 score on a scale — p=0.0007
Unemployment · Hazardous Drinking
Primary: Longest Duration of Alcohol Abstinence (Samples) (Physiological Measure) — 6.0; 11.0; 7.0; 7.5 number of alcohol negative breath tests — p=.028
First-Episode Psychosis
Primary: Number of Referrals to Correctional Health Services (CHS) — 8 Participants
Healthy
Primary: Adults of Groups 1, 2 and 3: Percentage of Participants With Serological Response to Vaccination as Measured by Virus Neutralization Assay (VNA) Titers at 28 Days After…
Obstructive Sleep Apnea
Primary: Number of Participants With Freedom From SleepFlex-related Serious Adverse Events — 10 Participants
Anxiety Disorders Generalized
Primary: Change in Worry Severity From Baseline to Post-intervention as Measured by the Penn State Worry Questionnaire (PSWQ) — 62.43; 6.19 units on a scale (PSWQ) — p=<0.005
Childhood Apraxia of Speech
Primary: Speech Sound Accuracy — 54.1; 32.5; 26.8; 42.1 Percent correct — p=.132
COVID-19 (Healthy Volunteers)
Primary: Geometric Mean Titers (GMTs) of Neutralizing Antibodies Against SARS-CoV-2 Recombinant Protein Vaccine Formulations at Day 1 — 5.00; 5.00; 5.00; 5.00 titers
Chronic Delta Hepatitis
Primary: Change From Baseline to Week 24 in Mean Hepatitis D Virus (HDV) Ribonucleic Acid (RNA) Titer — -1.62 log IU/mL
Bipolar Disorder · Schizophrenia · Schizoaffective Disorder
Primary: Feasibility of Combining ACT With 2 Different Varenicline-assisted Quitting Strategies — 1; 1; 9; 12 Participants
Ovarian Cancer
Primary: Progression Free Survival (PFS) of Combination Platinum Based Therapy With Anti-Programmed Death (PD)-1 Therapy Followed by Maintenance Anti-PD-1 Therapy in Patients…
Posttraumatic Stress Disorder · Depression
Primary: PTSD Checklist for DSM-5 (PCL-5) — 53.08 score on a scale
Urinary Tract Stone
Primary: Procedural Time (Minutes) — 20; 17 minutes
Heart Failure
Primary: Feasibility of Recruitment Procedures — 7 Participants