N/A N=60 Blood Flow Regulation in Individuals With Down Syndrome - Training Study
Down Syndrome
Primary: Change From Baseline Work Capacity at 13 Weeks — -1.20; -0.18 change in ml/kg/min — p=0.660
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=28 Study of Pembrolizumab With or Without Defactinib Following Chemotherapy as a Neoadjuvant and Adjuvant Treatment for Resectable Pancreatic Ductal Adenocarcinoma
Resectable Pancreatic Ductal Adenocarcinoma (PDAC) · Pancreatic Ductal Adenocarcinoma
Primary: Pathologic Complete Response (pCR) Rate — 0; 0 Percentage of participants
Phase 3 N=496 Patient-Reported Outcomes in Evaluating Lorecivivint (SM04690) for Moderate to Severe Knee Osteoarthritis (STRIDES-1)
Knee Osteoarthritis
Primary: Change From Baseline OA Pain in the Target Knee as Assessed by the Weekly Average of Daily Pain Numeric Rating Scale (NRS) at Week 12 — -2.15; -2.22 units on a scale…
N/A N=52 Clinical Study for TONOREF III Tested to ANSI Z80.10-2014
Intraocular Pressure
Primary: Agreement of Intraocular Pressure — 18.4; 18.3 mmHg
N/A N=10 Aldena STAR Particles
Healthy
Primary: Transepidermal Water Loss (TEWL) — 25.96; 20.44; 20.31; 23.82 g/m^2/hr
Phase 4 N=29 Lemborexant Shift Work Treatment Study
Shift-Work Related Sleep Disturbance
Primary: Daytime Total Sleep Time in Minutes Per Day Collected From the Consensus Sleep Diary — 362.7; 365.3 Minutes per day — p=0.884
N/A N=38 Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer
Bone Sarcoma · Childhood Cancer
Primary: Pain Intensity — -0.96; -0.56 Change in scores on a scale
N/A N=14 Team Science (The Liver Health Study)
Steatotic Liver Disease of Mixed Origin (MetALD)
Primary: Proportion Screened With Alcohol Intake and Weight-related Risks for Metabolism and Alcohol-associated Liver Disease — 26 Participants
Phase 4 N=1,000 A Study to Investigate Cardiac Troponin Levels After mRNA-1273.712 Vaccine in Participants 12 Through 30 Years of Age
Healthy Volunteers
Primary: Number of Participants With Elevated Cardiac Troponin I (cTnI) at Day 4 or Day 32 (3 Days After Injection 1 or Injection 2) — 1; 0 Participants
N/A N=94 Effectiveness of an Online Parenting Training
Behavior Problem · Behavior, Child · Parents
Primary: Aim 3: Change in Behavioral Assessment System Child Score — -3.17; 0.13 score on a scale
N/A N=21 Validity and Reliability of the 6-minute Walk Test Over a Distance of 6 Metres in People With Multiple Sclerosis
Multiple Sclerosis
Primary: The 6-minutes Walk Test on 6 Meters — 215.86; 221.57 m
Phase 1 N=60 An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment
Opioid Use Disorder · Chronic Pain
Primary: Retention — 3.7; 3.6 number of sessions attended
N/A N=32 Mechanisms and Phenotypes of Hypertension in Patients in Chronic Hemodialysis
Arterial Hypertension · Hemodialysis
Primary: Cardiac Output — 3.9; 4.10; 4.6 L/min
N/A N=104 Effectiveness and Safety Comparison of Lunaphil Ultra (Hyaluronic Acid, by Espad Pharmed Co.) Versus Juvederm Ultra 4® (Hyaluronic Acid, by Allergan Co.) in Nasolabial Folds (NLFs) Management
Moderate or Severe Nasolabial Folds
Primary: Mean Level of Improvement From Baseline in NLF Severity Score by Wrinkle Severity Rating Scale (WSRS) — -0.80; -0.81; -0.73; -0.74 score on a scale — p=>0.99
N/A N=90 NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial
Valvular Heart Disease · Aortic Valve Failure
Primary: Number of Participant That Experienced Technical Success With the TELLTALE Guidewire System — 90 Participants