Phase 2 N=157 Marijuana's Impact on Alcohol Motivation and Consumption
Alcohol Drinking · Marijuana
Primary: Alcohol Craving — 2.54; 2.64; 2.65; 2.55 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=179 A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
Obesity · Overweight and Obesity
Primary: Percent Change From Baseline in Body Weight at Week 32 — -0.85; -7.33; -15.6; -18.1 percent change
Phase 2 N=138 Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy for Stage III Non-small Cell Lung Cancer
Stage III Lung Non-Small Cell Cancer AJCC v7 · Stage IIIA Lung Non-Small Cell Cancer AJCC v7 · Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Primary: Percentage of Participants Alive Without Local-regional Progression [Local-regional Progression-free (LRPF) Survival] at Two Years (NRG) — 59.5; 54.6 percentage of…
Phase 2 N=189 Thymosin Alpha 1 to Prevent COVID-19 Infection in Renal Dialysis Patients
COVID-19
Primary: Number of Participants With COVID-19 Infection — 5; 7 participants
Phase 2 N=48 Quercetin Chemoprevention for Squamous Cell Carcinoma in Patients With Fanconi Anemia
Fanconi Anemia · Squamous Cell Carcinoma
Primary: Number of Participants With at Least 20% Reduction of Buccal Micronuclei — 13 Participants
Phase 2 N=600 Long-Term Safety Study of Tafenoquine
Healthy Volunteers
Primary: Serious Ophthalmic Safety Event — 45; 48 Participants
Phase 2 N=248 Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression
Treatment Resistant Depression
Primary: Change From Baseline to Week 4 in the Montgomery-Åsberg Depression Rating Scale (MADRS) Total Score. — -12.2; -11.6 units on a scale — p=0.7941
Phase 2 N=17 Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 Mutation
Leukemia · Leukemia, Myeloid · Monocytic Leukemia
Primary: Clinical Response: Hematological Improvement - Erythroid (HI-E) — 0; 0 participants
Phase 2 N=40 Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study
Lung Non-Small Cell Carcinoma · Stage I Lung Cancer AJCC v8 · Stage IA1 Lung Cancer AJCC v8
Primary: 6-month CT Assessment (Tumor Response Per mRECIST) — 1; 36; 2; 1 Participants
Phase 2 N=84 Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infection
Chronic Hepatitis B
Primary: Number of Subjects With Adverse Events as Assessed by CTCAE v5.0 — 9; 13; 3; 16 Participants
Phase 2 N=62 Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy
Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 · Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Primary: Pain-reduction Effects of Adding Venlafaxine to a Regimen of Gabapentin and Methadone to Control Pain During and After Chemoradiation — 8; 13; 39; 40 scores on a scale
Phase 2 N=51 Axitinib Monotherapy With Early Dynamic Contrast Enhanced Ultrasound Monitoring in Chemorefractory Third Line Metastatic Colorectal Cancer
Colorectal Cancer
Primary: Overall Survival — 175.0; 169.0 Days — p=0.0021
Phase 2 N=119 Magnetic Resonance Angiography for Peripheral Arterial Disease (PAD)
Peripheral Arterial Disease (PAD)
Primary: Segment-level Sensitivity and Specificity of VE-MRI at 3 Ferumoxytol Dosing Levels and Differences in Sensitivity and Specificity by Dose Group — 71.8; 76.8; 81.8; 71.2…
Phase 2 N=27 Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function
Primary Hyperoxaluria · Primary Hyperoxaluria Type 1 · Primary Hyperoxaluria Type 2
Primary: Percent Change From Baseline to Month 6 in Spot Urinary Oxalate-to-creatinine Ratio in PH1, PH2, or PH3 Participant Subgroups — -74.06; -68.34; -61.44; -17.98 Percent…
Phase 2 N=40 A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies
Adult Acute Lymphoblastic Leukemia in Remission · Adult Acute Myeloid Leukemia in Remission · Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Primary: Overall Survival (OS) in Patients With Haploidentical Family Donors With Hematological Malignancies in Morphological or Radiographic Remission or With Chemosensitive…