Phase 4 N=20 Effect of Atorvastatin on Bone-vascular Axis
Osteoporosis · Hypercholesterolemia
Primary: Relative Change in OPG/RANK/RANKL mRNA Expression in Isolated T Cells and Monocytes — 0.76 relative fold change — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=133 Interactions Between Drug Effects and Environments II
Substance-Related Disorders
Primary: Change in Time Spent in Drug-paired Room — 24.5; 6.2 seconds
Phase 4 N=24 Eluxadoline Bile Acid Malabsorption (BAM) Study
Irritable Bowel Syndrome With Diarrhea
Primary: Change From Baseline in Average Bristol Stool Form Scale (BSFS) Score Over 4 Weeks of Treatment Period — 5.89; 5.34; -1.25; -1.09 score on a scale
Phase 4 N=80 Spinal or Epidural Fentanyl or Sufentanil for Labour Pain in Early Phase of the Labour
Labor Pain
Primary: Change of Maximum Pain During Contraction at 20 Minutes After the Study Drug Delivery — 60; 36; 67; 42 mm
Phase 4 N=50 Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study
Cardiac Arrythmias
Primary: Tp-e — 69.5; 74.7 milliseconds
Phase 4 N=11 A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic
Hepatitis C, Chronic · Hepatitis C · Opiate Dependence
Primary: Percentage of Participants With Sustained Virologic Response at 12 Weeks Post Treatment (SVR-12) — 7 Participants
Phase 4 N=77 Wirelessly Observed Therapy in Comparison to Directly Observed Therapy for the Treatment of Tuberculosis
Tuberculosis
Primary: Step 1: Positive Detection Accuracy (PDA) — 99.3 percentage of DHFS detected doses
Phase 4 N=48 Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy
HIV Prevention · Transgender Health
Primary: Tenofovir Diphosphate Concentration in Dried Blood Spots (DBS) — 973.5; 1078 fmol/punch
Phase 4 N=37 A Study Comparing Fascia Iliaca Blockade vs Extracapsular Local Field Infiltration With Liposomal Bupivacaine
Femoro Acetabular Impingement
Primary: Visual Analogue Scale — 2.4; 2.7 cm
Phase 4 N=11 Varenicline Light Smoking Pilot
Smoking Cessation · Smoking Behaviors · Smoking
Primary: Change in Self-Reported Craving Level Via Lab-Based Cue Reactivity — 6.31; 4.2; 2.56; 2.4 score on a scale
Phase 4 N=30 Multi-center Study to Transplant Hepatitis-C Infected Kidneys
Renal Failure Chronic · Hepatitis C
Primary: Number of Participants With Undetectable HCV — 30 Participants
Phase 4 N=167 Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery
Surgical Site Infection
Primary: Culture Positivity — 14; 13; 63; 63 Participants
Phase 4 N=1 Psoriatic Oligoarthritis Intervention With Symptomatic thErapy
Psoriatic Arthritis
Primary: Number of Participants Who Are Eligible, Consent, and Complete the 48 Weeks Study — 0 Participants
Phase 4 N=159 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty
Osteoarthritis, Hip
Primary: Percentage Ambulating Early After Spinal Anesthesia — 9; 20; 35 Participants
Phase 4 N=2,176 Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo
Hypercholesterolemia
Primary: Change From Baseline in Cambridge Neuropsychological Test Automated Battery (CANTAB) Cognitive Domain Spatial Working Memory (SWM) Strategy Z-Score at Week 96 — -0.180…