65,437 trials
Heart Failure
Primary: Cmax — 8580; 2040 ng/mL
Emergency Contraception
Primary: Proportion of Dosing Instances Among User Population Taken Within 120 Hours (5 Days) of Most Recent Episode of Unprotected Sex. — 704 Dosing instances 120 hrs of…
Hearing Loss
Primary: Speech Intelligibility in Noise — 58; 80; 27; 50 percentage of words correctly repeated — p=<0.01
Myopia
Primary: Diameter of the Pupil Measured With a Neuroptix Pupillometer — 4.9; 5.1; 5.9; 5.9 millimeters — p=0.002
Fibromyalgia
Primary: Change From Baseline to Week 14 in the Numerical Rating Scale (NRS) Weekly Average of Daily Self-reported Average Pain Severity Scores. — -1.6; -1.3 score on a scale…
Post Traumatic Stress Disorder · Problem Drinking
Primary: Problem Drinking Scores at Baseline and 3 Weeks — 12.40; 11.00; 10.16; 7.62 score on a scale — p=.60
Fibrodysplasia Ossificans Progressiva
Primary: Period 1: Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Serious TEAEs — 24; 20; 2; 4 Participants
Nicotine Dependence, Cigarettes
Primary: Nicotine Beliefs — 7.5; 7.8; 10.9; 11.3 score on a scale
Anal Cancer · High-grade Squamous Intraepithelial Lesion · HIV Infection
Primary: Anal Cancer Incidence — 173; 402 cases per 100,000 person years
Diamond Blackfan Anemia · Blackfan Diamond Syndrome · DBA
Primary: Response to Leucine in Transfusion Dependent Patients With Diamond Blackfan Anemia — 2; 5; 36; 0 Participants
PTSD
Primary: PCL-5 Symptom Score — 73.32; 72.95 score on a scale
COVID-19 · SARS-CoV 2
Primary: Percent of Healthcare Workers Testing Positive for COVID-19. — 0; 0 percentage of healthcare workers
Pneumococcal Infections
Primary: Percentage of Participants With a Solicited Injection-site Adverse Event — 60.0; 65.5; 57.0; 59.1 Percentage of participants — p== 0.050
Tobacco Use Disorder
Primary: Cigarettes Per Day (CPD) — 25.28; 19.95; 17.74 cigarettes per day — p=<0.0001
Tobacco Use Cessation
Primary: 7-day Point-prevalence Abstinence — 21.5; 15.8 Percentage of participants quit at 1-mo