65,437 trials
Asthma
Primary: Percentage of Participants Achieving Meaningful Asthma Improvement at the End of 12-Week Treatment Period — 54.6; 61.33 percentage of participants
Allergic Rhinitis · Conjunctivitis
Primary: Combined Symptom and Medication Score (CSMS) in Participants Who Receive a Single Dose of REGN5713-5714-5715 Versus Placebo — 7.503; 8.498 Scores on a Scale — p=0.0497
Smallpox Vaccine Adverse Reaction
Primary: Number of Vaccinated Participants With Adverse Events (AEs) Including Serious Adverse Events (SAEs) — 1420 Participants
Metastatic Renal Cell Carcinoma · Advanced Urothelial Carcinoma · Advanced Gastric Adenocarcinoma
Primary: Phase 1b: Number of Participants With Dose-Limiting Toxicities (DLTs) in Cohorts 1 to 6 — 0; 1; 0; 0 Participants
Decision Making
Primary: Change in D' Between Pairs of Blocks. — -0.138; .0754; 0.023; -.129 z-score
Neovascular Age-related Macular Degeneration
Primary: Mean Change From Baseline in Best Corrected Visual Acuity (BCVA) Per the Early Treatment Diabetic Retinopathy Study (ETDRS) Testing Method — 10.4; 6.7; 13.7 score on a…
Breast Neoplasms
Primary: Pathologic Complete Response (pCR) — 25 Participants
HER2-positive Breast Cancer · Early-stage Breast Cancer · Breast Cancer
Primary: Immunogenicity Assessments (ADA and Nab) — 3; 2; 3; 0 Participants
Primary Open Angle Glaucoma
Primary: Number of Participants With > 20% Decrease in Mean Diurnal Intraocular Pressure — 216; 96 Participants
Arthritis, Rheumatoid
Primary: Change From Baseline in Vascular Inflammation as Measured by FDG-PET/CT at 6 Months — -0.19; -0.24 ratio — p=0.79
Chronic Pain
Primary: Change in Pain Intensity — -1.61; -1.35 score on a scale — p=0.809
Contact Lens Wear
Primary: Mean Distance High-contrast logMAR Lens VA — -0.057; -0.059 LogMAR
Autism
Primary: Primary Outcome Measurements to Determine Efficacy of Treatment With CM-AT Versus Placebo for Changes in the Aberrant Behavior Checklist Subscale for Irritability /…
Laser Assisted Liposuction
Primary: Correct Identification of Before and After Photographs — 20 Participants
Insomnia
Primary: Change in Sleep Difficulties Assessed by the Insomnia Severity Index — -3.6; -10.0; -9.3 score on a scale