65,437 trials
Pain Interference · Depression · Antiretroviral Adherence
Primary: Brief Pain Inventory Interference Scale at 3 Months — 5.03; 4.23 score on a scale — p=0.008
Plaque Psoriasis
Primary: Percent of Subjects Who Achieve a Physician Global Assessment (PGA) Score of Clear (0) or Almost Clear (1) With a Minimum 2-grade Improvement From Baseline at Week 12…
Hepatic Cirrhosis · Liver Fibrosis · Nonalcoholic Fatty Liver Disease (NAFLD)
Primary: The Percentage of Participants Who Achieve a ≥ 1-Stage Improvement in Fibrosis Without Worsening of Nonalcoholic Steatohepatitis (NASH) at Week 48 — 28.2; 24.3; 28.2…
Breast - Female · Male Breast Cancer
Primary: Number of Participants With at Least One Grade 3 or 4 Treatment-related Adverse Event — 5; 6 Participants
Sedentary Lifestyle · Self-control
Primary: Objective Physical Activity — 6184.45; 6671.81; 6647.71; 6932.25 Average Daily Steps — p=0.038
Hypoactive Sexual Desire Disorder · Sexual Dysfunction · Female Sexual Dysfunction
Primary: Feasibility - Number of Enrolled Women Participating in All Sessions — 15; 22 Participants — p=0.027
Plaque Psoriasis
Primary: Percent of Subjects Who Achieve a Physician Global Assessment (PGA) Score of Clear (0) or Almost Clear (1) With a Minimum 2-grade Improvement From Baseline at Week 12…
Pancreatic Cancer
Primary: The Maximum Tolerated Dose (MTD) of Stereotactic Body Radiotherapy (SBRT) in Locally Advanced Pancreatic Cancer (LAPC) Patients Who Have Not Developed Distant…
Smoking, Tobacco
Primary: Performance Variable - Correlation of Carbon Monoxide (CO) Measurements Between COBSS and Predicate Devices — 0.9878 Correlation coefficient (R-value)
Migraine
Primary: Percentage of Participants With Freedom From Pain at 2 Hours Post-dose — 19.6; 22.5; 23.1; 15.5 percentage of participants — p=0.1214
Essential Tremor
Primary: Digital Spirography — 1.04; 1.00 millimeters of tremor amplitude
COVID-19
Primary: Change From Baseline in the Amount of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Virus RNA for AT-527 550 mg and Matched Placebo — -1.16; -1.26; -2.42…
Smoking Cessation · Smoking, Cigarette · Nicotine Dependence
Primary: Change in Smoking Intensity — -8.49; -6.79 change in cigarettes per day — p=0.05
Acute Coronary Syndrome
Primary: Composite of Cardiovascular Death, Resuscitated Cardiac Arrest, Non-Fatal Myocardial Infarction, and Non-Fatal Stroke — 327; 292 Participants — p=0.12
Asthma
Primary: Absolute Weighted Mean of Forced Expiratory Volume in 1 Second (FEV1) (0-4 Hours) at Week 12 in 5-17 Year Old Population — 2.082; 1.994 Liters — p=<0.001