Phase 4 N=182 Immunogenicity of Hepatitis B Vaccination in HIV-infected Adults
Hepatitis B Vaccine
Primary: Number and Percentage of Participants With Anti-HBs Seroconversion at Month 7 — 75; 69 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=40 Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery
Endoscopic Sinus Surgery · Nasal Polyps
Primary: Surgical Field Visualization During Sinus Surgery as Indicated by Score on Boezaart Grading Scale — 3; 2.55 score on a scale
Phase 4 N=100 Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
Major Depressive Disorder · Dysthymic Disorder · Depressive Disorder, NOS
Primary: Hamilton Rating Scale for Depression (HRSD) — 13.3 score on a scale
Phase 4 N=498 A Research Study to Compare the Effect of Insulin Degludec and Insulin Glargine on Blood Sugar Levels in People With Type 2 Diabetes - the SWITCH PRO Study
Diabetes Mellitus, Type 2
Primary: Percentage of Time Spent in Glycaemic Target Range 70-180 mg/dL (3.9-10.0 mmol/L) Both Inclusive, Using Flash Glucose Monitoring (FGM) — 72.11; 70.68 Percentage of Time…
Phase 4 N=37 Large-scale Brain Organization During Cognitive Control in ADHD
Attention Deficit Hyperactivity Disorder
Primary: Resting State Brain Network Organization — 0.223; 0.228 units on a scale — p=0.532
Phase 4 N=80 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis
Non-allergic Rhinitis
Primary: Change in Visual Analogue Scale for Major Nasal Symptoms — 3.66; 4.29; 4.49; 5.6 score on a scale
Phase 4 N=51 The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery
Post-operative Pain · Colon Cancer · Diverticulitis
Primary: PCA (Patient Controlled Analgesia) Usage
Phase 4 N=177 Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM
Anal Chlamydia Infection
Primary: The Proportion of Subjects With Microbiologic Cure (Negative Rectal CT NAAT Result) at Day 29 — 0.74; 1.00 proportion of participants — p=<0.001
Phase 4 N=85 Multimodal Analgesia With Acetaminophen vs. Narcotics Alone After Hip Arthroscopy
Hip Arthroscopy
Primary: Patient Satisfaction — 8.48; 8.83 score on a scale
Phase 4 N=21 Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
Pain, Postoperative
Primary: Total Narcotic Usage — 0.8; .13; 0.18 mg/kg/day morphine
Phase 4 N=224 Benefits of Insulin Supplementation for Correction of Hyperglycemia in Patients With Type 2 Diabetes
Diabetes Mellitus, Type 2
Primary: Mean Daily BG Levels — 172; 173 mg/dL
Phase 4 N=186 Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections
C-Section · Pain Management
Primary: Total Postsurgical Opioid Consumption Through 72 Hours After TAP Infiltration During Elective Cesarean Section — 15.5; 32.0 MED, mg — p=0.0117
Phase 4 N=50 Study of Memantine to Treat Huntington's Disease
Huntington's Disease
Primary: Change in the Hopkins Verbal Learning Test - Revised for Delayed Recall (HVLT-R-delayed Recall)
Phase 4 N=337 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation
Acute Respiratory Failure · Intubation Complication
Primary: Number of Participants With Cardiovascular Collapse — 33; 31 Participants
Phase 4 N=36 Eszopiclone in the Treatment of Insomnia and Fibromyalgia
Fibromyalgia · Insomnia
Primary: Change in Total Sleep Time (TST) as Recorded in Patient Diaries — 68.72; 13.47 minutes