65,437 trials
Alzheimers Disease · Dementia · Alzheimers Disease, Familial
Primary: Assess Cognitive Efficacy in Individuals With Mutations Causing Dominantly Inherited AD as Measured by the DIAN-Multivariate Cognitive Endpoint (DIAN-MCE); — 1.063…
Seroma
Primary: Total Drain Output — 284; 317 ml
Autoimmune Hemolytic Anemia
Primary: Percentage of Participants Attaining a Complete Response at Any Visit From Week 6 to Week 12 — 20.0; 40.0 percentage of participants
Metastatic Prostate Adenocarcinoma
Primary: Evaluate Equivalence Between 68GA-PSMA-cyclotron and 68Ga-PSMA-generator Across Varying Pathologic Lesions — 0.98; 0.98; 0.99; 0.99 ICC estimate
Fibromyalgia
Primary: Brain Neurocircuitry Underlying Chronic Pain (Percent of Time of a Somato-sensory Cortex Coactivation Pattern) — 0.1281; 0.1190; 0.1213; 0.1345 percentage of scan time…
Myelodysplastic Syndrome · Leukemia, Myelomonocytic, Chronic · Leukemia, Myeloid, Acute
Primary: Event-Free Survival (EFS) — 15.7; 17.7 months — p==0.557
Esophageal Adenocarcinoma · Barrett's Esophagus · Reflux Esophagitis
Primary: Reduction of F. Nucleatum in Saliva
Amyloidosis · Plasma Cell Myeloma
Primary: Maximum Tolerated (MTD) Dose of Cyclophosphamide With Ixazomib and Dexamethasone (Phase I) — 4; 40 mg weekly
Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53
Primary: Phase Ib: Dose-limiting Toxicities (DLT) (See Description) of Combined APR-246 and Carboplatin/PLD Regimen — 0; 1; 0 Participants
Crohn's Disease
Primary: Percentage of Participants With Enhanced Clinical Response in the Induction Phase at Week 10 — 24.3; 19.4 percentage of participants — p==0.347
Presbyopia
Primary: Number of Eyes With Monocular Uncorrected Near Visual Acuity of 20/40 or Better at 40 cm 6 Months After Implantation — 66 Eyes
COPD
Primary: Occurrence of Suboptimal PIFR — 22.7 percentage of participants
Tibial Tubercle Osteotomy
Primary: Perioperative Blood Loss — 67.8; 56.15 mL
Cancer · Hypertension · Diabetes
Primary: Change in Fatigue as Assessed by Patient-Reported Outcomes Measurement Information System (PROMIS) Short Form v1.0-Fatigue 6a — -1.61; 4.26 T-score
Abdominoplasty
Primary: Mean (Peak) Plasma Concentration (Cmax) — 0; 573 ng/mL